Megestrol acetate for anorexia and cachexia

C. Loprinzia, B. P.A. Johnson, C. M. Jensen

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Based on promising preliminary information obtained from uncontrolled pilot studies, several randomized, placebo-controlled, double-blind clinical trials have been launched to evaluate the effectiveness of megestrol acetate for the treatment of patients with anorexia and/or cachexia. The results of these studies have demonstrated that megestrol acetate can improve patients' appetites and promote nonfluid weight gain in some. They also suggest that megestrol acetate has antiemetic properties. Ongoing clinical trials are evaluating the dose-response relationship of megestrol acetate for these clinical problems and whether megestrol acetate will improve the survival of patients at risk for developing cancer anorexia/cachexia.

Original languageEnglish (US)
Pages (from-to)46-49
Number of pages4
Issue numberSUPPL. 2
StatePublished - Jan 1 1992


  • Anorexia/cachexia
  • Megestrol acetate

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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