TY - JOUR
T1 - Medical Comorbidity of Attention-Deficit/Hyperactivity Disorder in US Adolescents
AU - Jameson, Nicole D.
AU - Sheppard, Brooke K.
AU - Lateef, Tarannum M.
AU - Vande Voort, Jennifer L.
AU - He, Jian Ping
AU - Merikangas, Kathleen Ries
N1 - Publisher Copyright:
© SAGE Publications.
PY - 2016/10/1
Y1 - 2016/10/1
N2 - Understanding patterns of medical comorbidity in attention-deficit/hyperactivity disorder (ADHD) may lead to better treatment of affected individuals as well as aid in etiologic study of disease. This article provides the first systematic evaluation on the medical comorbidity of ADHD in a nationally representative sample (National Comorbidity Replication Survey-Adolescent Supplement; N = 6483) using formal diagnostic criteria. Survey-weighted odds ratios adjusted for demographics, additional medical, and mental disorders were calculated for associations between ADHD and medical conditions. Models adjusted for demographics revealed significantly increased odds of allergy, asthma, enuresis, headache/migraine, and serious stomach or bowel problems. After adjusting for comorbidity, across the medical conditions, enuresis and serious stomach problems were the strongest correlates of ADHD. These findings confirm the pervasive medical comorbidity of ADHD reported in previous clinical and community-based studies. The intriguing salience of enuresis and serious stomach or bowel conditions may also provide an important clue to multisystem involvement in ADHD.
AB - Understanding patterns of medical comorbidity in attention-deficit/hyperactivity disorder (ADHD) may lead to better treatment of affected individuals as well as aid in etiologic study of disease. This article provides the first systematic evaluation on the medical comorbidity of ADHD in a nationally representative sample (National Comorbidity Replication Survey-Adolescent Supplement; N = 6483) using formal diagnostic criteria. Survey-weighted odds ratios adjusted for demographics, additional medical, and mental disorders were calculated for associations between ADHD and medical conditions. Models adjusted for demographics revealed significantly increased odds of allergy, asthma, enuresis, headache/migraine, and serious stomach or bowel problems. After adjusting for comorbidity, across the medical conditions, enuresis and serious stomach problems were the strongest correlates of ADHD. These findings confirm the pervasive medical comorbidity of ADHD reported in previous clinical and community-based studies. The intriguing salience of enuresis and serious stomach or bowel conditions may also provide an important clue to multisystem involvement in ADHD.
KW - ADHD
KW - Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition
KW - National Comorbidity Replication Survey-Adolescent Supplement
KW - comorbidity
KW - enuresis
UR - http://www.scopus.com/inward/record.url?scp=84987723696&partnerID=8YFLogxK
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U2 - 10.1177/0883073816653782
DO - 10.1177/0883073816653782
M3 - Article
C2 - 27334310
AN - SCOPUS:84987723696
SN - 0883-0738
VL - 31
SP - 1282
EP - 1289
JO - Journal of child neurology
JF - Journal of child neurology
IS - 11
ER -