Mechanisms of endocardial endothelium modulation of myocardial performance

P. Mohan, S. U. Sys, D. L. Brutsaert, E. L. Ritman, W. Barry, J. Janicki, J. Bassingthwaighte, J. Solaro, H. E.D.J. Ter Keurs, T. Arts

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

The endocardial endothelium (EE) modulates the performance of the subjacent myocardium and plays an important role in regulation of cardiac function. This modulation has been confirmed in a number of different species and in both in vitro and in vivo conditions. The mechanisms of EE modulation of myocardial performance are still under investigation and the possibilities include the role of EE as a transendothelial physicochemical barrier and/or the release of various chemical messengers by the EE.

Original languageEnglish (US)
Pages (from-to)249-260
Number of pages12
JournalAdvances in experimental medicine and biology
Volume382
DOIs
StatePublished - 1995

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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