Mechanisms of Arrhythmias and Conduction Disorders in Older Adults

Mahek Mirza, Anton Strunets, Win Kuang Shen, Arshad Jahangir

Research output: Contribution to journalReview article

34 Scopus citations

Abstract

Aging is associated with an increased prevalence of cardiac arrhythmias, which contribute to higher morbidity and mortality in the elderly. The frequency of cardiac arrhythmias, particularly atrial fibrillation and ventricular tachyarrhythmia, is projected to increase as the population ages, greatly impacting health care resource utilization. Several clinical factors associated with the risk of arrhythmias have been identified in the population, yet the molecular bases for the increased predisposition to arrhythmogenesis in the elderly are not fully understood. This review highlights the epidemiology of cardiac dysrhythmias, changes in cardiac structure and function associated with aging, and the basis for arrhythmogenesis in the elderly.

Original languageEnglish (US)
Pages (from-to)555-573
Number of pages19
JournalClinics in Geriatric Medicine
Volume28
Issue number4
DOIs
StatePublished - Nov 2012

Keywords

  • Aging
  • Arrhythmias
  • Atrial fibrillation
  • Elderly
  • Mechanisms
  • Sudden cardiac death
  • Ventricular fibrillation

ASJC Scopus subject areas

  • Geriatrics and Gerontology

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