TY - JOUR
T1 - Mechanisms of adverse cardiometabolic consequences of obesity
AU - Diaz-Melean, Carlos M.
AU - Somers, Virend K.
AU - Rodriguez-Escudero, Juan P.ablo
AU - Singh, Prachi
AU - Sochor, Ondrej
AU - Llano, Ernesto M.anuel
AU - Lopez-Jimenez, Francisco
N1 - Funding Information:
Prachi Singh, Virend K. Somers, Ondrej Sochor, and Francisco Lopez-Jimenez were supported by the European Regional Development Fund, project FNUSA-ICRC (Z.1.05/1.1.00/02.0123). Ondrej Sochor was also supported by the Internal Grant Agency of the Ministry of Health of the Czech Republic (IGA MZČR; NT 13434-4/2012). Prachi SIngh is funded by 11SDG726004 from American Heart Association (AHA).
PY - 2013/11/1
Y1 - 2013/11/1
N2 - Obesity is an epidemic that threatens the health of millions of people worldwide and is a major risk factor for cardiovascular diseases, hypertension, diabetes, and dyslipidemia. There are multiple and complex mechanisms to explain how obesity can cause cardiovascular disease. In recent years, studies have shown some limitations in the way we currently define obesity and assess adiposity. This review focuses on the mechanisms involved in the cardiometabolic consequences of obesity and on the relationship between obesity and cardiovascular comorbidities, and provides a brief review of the latest studies focused on normal weight obesity and the obesity paradox.
AB - Obesity is an epidemic that threatens the health of millions of people worldwide and is a major risk factor for cardiovascular diseases, hypertension, diabetes, and dyslipidemia. There are multiple and complex mechanisms to explain how obesity can cause cardiovascular disease. In recent years, studies have shown some limitations in the way we currently define obesity and assess adiposity. This review focuses on the mechanisms involved in the cardiometabolic consequences of obesity and on the relationship between obesity and cardiovascular comorbidities, and provides a brief review of the latest studies focused on normal weight obesity and the obesity paradox.
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U2 - 10.1007/s11883-013-0364-2
DO - 10.1007/s11883-013-0364-2
M3 - Review article
C2 - 24048571
AN - SCOPUS:84899035650
SN - 1523-3804
VL - 15
JO - Current atherosclerosis reports
JF - Current atherosclerosis reports
IS - 11
M1 - 364
ER -