Measuring bladder viscoelasticity using ultrasound

Ivan Z. Nenadic, Bo Qiang, Matthew W. Urban, Alireza Nabavizadeh, James F. Greenleaf, Mostafa Fatemi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Increase in bladder stiffness is associated with various pathological conditions. Measuring bladder viscoelasticity could be an important step towards understanding various disease processes and improving patient care. Here, we introduce Ultrasound Bladder Vibrometry (UBV), a novel method for rapid and noninvasive measurement of bladder wall viscoelasticity. UBV uses acoustic radiation force to excite Lamb waves in the bladder wall and track the motion using ultrasound pulse-echo techniques. Fourier space analysis of the tissue motion is used to calculate the Lamb wave velocity dispersion (change of phase velocity as a function of frequency). The measured phase velocity dispersion is fit with the antisymmetric Lamb wave model to estimate tissue elasticity and viscosity. Finite element analysis of viscoelastic plates was used to study the effect of curvature on Lamb wave dispersion. The feasibility of the UBV technique was demonstrated in ex vivo and in vivo settings.

Original languageEnglish (US)
Title of host publication2012 IEEE International Ultrasonics Symposium, IUS 2012
Pages105-108
Number of pages4
DOIs
StatePublished - Dec 1 2012
Event2012 IEEE International Ultrasonics Symposium, IUS 2012 - Dresden, Germany
Duration: Oct 7 2012Oct 10 2012

Publication series

NameIEEE International Ultrasonics Symposium, IUS
ISSN (Print)1948-5719
ISSN (Electronic)1948-5727

Other

Other2012 IEEE International Ultrasonics Symposium, IUS 2012
CountryGermany
CityDresden
Period10/7/1210/10/12

Keywords

  • In vivo bladder ultrasound
  • bladder elasticity and viscosity

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

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