TY - GEN
T1 - Measuring bladder viscoelasticity using ultrasound
AU - Nenadic, Ivan Z.
AU - Qiang, Bo
AU - Urban, Matthew W.
AU - Nabavizadeh, Alireza
AU - Greenleaf, James F.
AU - Fatemi, Mostafa
PY - 2012
Y1 - 2012
N2 - Increase in bladder stiffness is associated with various pathological conditions. Measuring bladder viscoelasticity could be an important step towards understanding various disease processes and improving patient care. Here, we introduce Ultrasound Bladder Vibrometry (UBV), a novel method for rapid and noninvasive measurement of bladder wall viscoelasticity. UBV uses acoustic radiation force to excite Lamb waves in the bladder wall and track the motion using ultrasound pulse-echo techniques. Fourier space analysis of the tissue motion is used to calculate the Lamb wave velocity dispersion (change of phase velocity as a function of frequency). The measured phase velocity dispersion is fit with the antisymmetric Lamb wave model to estimate tissue elasticity and viscosity. Finite element analysis of viscoelastic plates was used to study the effect of curvature on Lamb wave dispersion. The feasibility of the UBV technique was demonstrated in ex vivo and in vivo settings.
AB - Increase in bladder stiffness is associated with various pathological conditions. Measuring bladder viscoelasticity could be an important step towards understanding various disease processes and improving patient care. Here, we introduce Ultrasound Bladder Vibrometry (UBV), a novel method for rapid and noninvasive measurement of bladder wall viscoelasticity. UBV uses acoustic radiation force to excite Lamb waves in the bladder wall and track the motion using ultrasound pulse-echo techniques. Fourier space analysis of the tissue motion is used to calculate the Lamb wave velocity dispersion (change of phase velocity as a function of frequency). The measured phase velocity dispersion is fit with the antisymmetric Lamb wave model to estimate tissue elasticity and viscosity. Finite element analysis of viscoelastic plates was used to study the effect of curvature on Lamb wave dispersion. The feasibility of the UBV technique was demonstrated in ex vivo and in vivo settings.
KW - In vivo bladder ultrasound
KW - bladder elasticity and viscosity
UR - http://www.scopus.com/inward/record.url?scp=84882301473&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84882301473&partnerID=8YFLogxK
U2 - 10.1109/ULTSYM.2012.0026
DO - 10.1109/ULTSYM.2012.0026
M3 - Conference contribution
AN - SCOPUS:84882301473
SN - 9781467345613
T3 - IEEE International Ultrasonics Symposium, IUS
SP - 105
EP - 108
BT - 2012 IEEE International Ultrasonics Symposium, IUS 2012
T2 - 2012 IEEE International Ultrasonics Symposium, IUS 2012
Y2 - 7 October 2012 through 10 October 2012
ER -