Measurements of RF heating during 3.0-T MRI of a pig implanted with deep brain stimulator

Krzysztof R. Gorny, Michael F. Presti, Stephan J. Goerss, Sun C. Hwang, Dong Pyo Jang, Inyong Kim, Hoon Ki Min, Yunhong Shu, Christopher P. Favazza, Kendall H. Lee, Matt A. Bernstein

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

Purpose: To present preliminary, in vivo temperature measurements during MRI of a pig implanted with a deep brain stimulation (DBS) system. Materials and Methods: DBS system (Medtronic Inc., Minneapolis, MN) was implanted in the brain of an anesthetized pig. 3.0-T MRI was performed with a T/R head coil using the low-SAR GRE EPI and IR-prepped GRE sequences (SAR: 0.42 and 0.39. W/kg, respectively), and the high-SAR 4-echo RF spin echo (SAR: 2.9. W/kg). Fluoroptic thermometry was used to directly measure RF-related heating at the DBS electrodes, and at the implantable pulse generator (IPG). For reference the measurements were repeated in the same pig at 1.5. T and, at both field strengths, in a phantom. Results: At 3.0. T, the maximal temperature elevations at DBS electrodes were 0.46. °C and 2.3. °C, for the low- and high-SAR sequences, respectively. No heating was observed on the implanted IPG during any of the measurements. Measurements of in vivo heating differed from those obtained in the phantom. Conclusion: The 3.0-T MRI using GRE EPI and IR-prepped GRE sequences resulted in local temperature elevations at DBS electrodes of no more than 0.46. °C. Although no extrapolation should be made to human exams and much further study will be needed, these preliminary data are encouraging for the future use 3.0-T MRI in patients with DBS.

Original languageEnglish (US)
Pages (from-to)783-788
Number of pages6
JournalMagnetic Resonance Imaging
Volume31
Issue number5
DOIs
StatePublished - 2013

Keywords

  • 3.0T
  • DBS
  • Deep brain stimulation
  • FMRI
  • MRI
  • Medical device safety

ASJC Scopus subject areas

  • Biophysics
  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'Measurements of RF heating during 3.0-T MRI of a pig implanted with deep brain stimulator'. Together they form a unique fingerprint.

  • Cite this

    Gorny, K. R., Presti, M. F., Goerss, S. J., Hwang, S. C., Jang, D. P., Kim, I., Min, H. K., Shu, Y., Favazza, C. P., Lee, K. H., & Bernstein, M. A. (2013). Measurements of RF heating during 3.0-T MRI of a pig implanted with deep brain stimulator. Magnetic Resonance Imaging, 31(5), 783-788. https://doi.org/10.1016/j.mri.2012.11.005