Measurement of murine serum amyloid P component by rate nephelometry

Morie Gertz, Jean D. Sipe, Martha Skinner, Alan S. Cohen, Robert A. Kyle

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Murine serum amyloid P component (SAP) is an acute-phase protein that is increased 2-10-fold in concentration following appropriate inflammatory or infections stimuli. Previous studies of the acute-phase SAP response have employed quantitative immunoelectrophoresis or radioimmunoassay to measure SAP concentration. A rate nephelometric procedure has been developed which measures SAP concentration rapidly and with equivalent or greater precision than the previously applied techniques. This simple method will facilitate experimental and clinical studies of the acute-phase response.

Original languageEnglish (US)
Pages (from-to)173-180
Number of pages8
JournalJournal of Immunological Methods
Volume69
Issue number2
DOIs
StatePublished - Apr 27 1984

Keywords

  • acute-phase response
  • nephelometry
  • serum amyloid P (SAP)

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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