Measurement of Gastrointestinal and Colonic Motor Functions in Humans and Animals

Research output: Contribution to journalReview article

17 Citations (Scopus)

Abstract

The ability to assess the complex motor functions of the gastrointestinal tract accurately has been of tremendous value to understanding and treating digestive diseases. Unlike other smooth or cardiac muscle organ systems with relatively more rhythmic and patterned motor behavior, the complexity of the diverse motor behaviors of the alimentary canal have made the development and use of clinical and preclinical tests of gastrointestinal motor function a great challenge. It is perhaps this complexity, as well as the importance of gastrointestinal function to overall health and well-being, that have fascinated early physiologists and continue to push modern physiologists and clinical diagnosticians to develop new and more accurate measurements of motility. It is also because of this complexity that the standardization of these measures presents hurdles to broad adoption and that the measurements of the more complex motility functions remain restricted mainly to tertiary referral centers.

Original languageEnglish (US)
Pages (from-to)412-428
Number of pages17
JournalCMGH Cellular and Molecular Gastroenterology and Hepatology
Volume2
Issue number4
DOIs
StatePublished - Jul 1 2016

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Aptitude
Tertiary Care Centers
Smooth Muscle
Gastrointestinal Tract
Myocardium
Health

Keywords

  • Acute Pancreatitis
  • Apoptosis
  • Biliary Pancreatitis
  • Necroptosis
  • Pancreatic Cell Death

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology

Cite this

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abstract = "The ability to assess the complex motor functions of the gastrointestinal tract accurately has been of tremendous value to understanding and treating digestive diseases. Unlike other smooth or cardiac muscle organ systems with relatively more rhythmic and patterned motor behavior, the complexity of the diverse motor behaviors of the alimentary canal have made the development and use of clinical and preclinical tests of gastrointestinal motor function a great challenge. It is perhaps this complexity, as well as the importance of gastrointestinal function to overall health and well-being, that have fascinated early physiologists and continue to push modern physiologists and clinical diagnosticians to develop new and more accurate measurements of motility. It is also because of this complexity that the standardization of these measures presents hurdles to broad adoption and that the measurements of the more complex motility functions remain restricted mainly to tertiary referral centers.",
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AB - The ability to assess the complex motor functions of the gastrointestinal tract accurately has been of tremendous value to understanding and treating digestive diseases. Unlike other smooth or cardiac muscle organ systems with relatively more rhythmic and patterned motor behavior, the complexity of the diverse motor behaviors of the alimentary canal have made the development and use of clinical and preclinical tests of gastrointestinal motor function a great challenge. It is perhaps this complexity, as well as the importance of gastrointestinal function to overall health and well-being, that have fascinated early physiologists and continue to push modern physiologists and clinical diagnosticians to develop new and more accurate measurements of motility. It is also because of this complexity that the standardization of these measures presents hurdles to broad adoption and that the measurements of the more complex motility functions remain restricted mainly to tertiary referral centers.

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