Meal fatty acid uptake in adipose tissue: Gender effects in nonobese humans

Susan A. Romanski, Rita M. Nelson, Michael D. Jensen

Research output: Contribution to journalArticlepeer-review

104 Scopus citations

Abstract

We tested for gender differences in dietary fatty acid metabolism in 12 nonobese men and 12 nonobese women using the meal fatty acid tracer/adipose tissue biopsy study design. In addition to determining body composition, measurements of regional adipose tissue lipoprotein lipase activity, blood flow, and fat cell size were performed to place the meal fatty acid kinetic studies in perspective. Twenty-four hours after ingesting the test meal, the concentration of meal fatty acids was greater (P < 0.05) in abdominal subcutaneous than in thigh adipose tissue in both men (0.61 ± 0.12 vs. 0.45 ± 0.09 mg/g) and women (0.59 ± 0.10 vs. 0.43 ± 0.05) but was not different between men and women. A greater percentage of dietary fat was stored in subcutaneous adipose tissue in women than in men (38 ± 3 vs. 24 ± 3%, respectively, P < 0.05), and a greater portion of meal fatty acid disposal was unaccounted for in men. Significant gender differences in regional adipose tissue blood flow after meal ingestion were noted; the differences were in the direction that could support greater nutrient storage in lower body fat in women.

Original languageEnglish (US)
Pages (from-to)E455-E462
JournalAmerican Journal of Physiology - Endocrinology and Metabolism
Volume279
Issue number2 42-2
DOIs
StatePublished - 2000

Keywords

  • Adipose tissue blood flow
  • Body composition
  • Visceral fat
  • [C]triolein

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Physiology
  • Physiology (medical)

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