Mature teratoma of the uterine cervix with pulmonary differentiation

Andras Khoor, M. V. Fleming, C. A. Purcell, J. D. Seidman, A. H. Ashton, D. L. Weaver

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

Teratomas of the uterus are very rare, and a uterine teratoma with pulmonary differentiation has not, to our knowledge, been described previously. In this article, we report such a case in a 33-year-old woman, who presented with heavy vaginal bleeding and a polypoid mass of the uterine cervix. The cervical lesion was composed entirely of mature lung tissue, including bronchial, bronchiolar, and alveolar structures. The presence of well-differentiated respiratory epithelial cells, ie, Clara cells and alveolar type II cells, is confirmed by immunohistochemistry. The patient had no history of dilatation and curettage; therefore, implantation of fetal tissue could be excluded from the differential diagnoses. Since this is a newly developed mass in an adult individual, we favor a neoplastic process over heterotopia and interpret the lesion as unilateral lung development in an extragonadal mature teratoma.

Original languageEnglish (US)
Pages (from-to)848-850
Number of pages3
JournalArchives of Pathology and Laboratory Medicine
Volume119
Issue number9
StatePublished - 1995
Externally publishedYes

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

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