Marrow fibrosis associated with a Philadelphia chromosome

Peter C. Nowell, Jeffrey A. Kant, Janet B. Finan, Peter A. Cassileth, Curtis A. Hanson

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Three patients had marked marrow fibrosis and an apparent Philadelphia (Ph) chromosome. Hematologic, cytogenetic, and molecular studies demonstrated the heterogeneity of such cases, including the first example of clinically typical myelofibrosis (MF) associated with a bcr gene rearrangement characteristic of chronic myelogenous leukemia (CML).

Original languageEnglish (US)
Pages (from-to)89-92
Number of pages4
JournalCancer Genetics and Cytogenetics
Issue number1
StatePublished - Mar 1992

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research


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