Marital status and quality of life in patients with esophageal cancer or Barrett's Esophagus: The Mayo Clinic Esophageal Adenocarcinoma and Barrett's Esophagus registry study

Robert C. Miller, Pamela J. Atherton, Brian F. Kabat, Mary B. Fredericksen, Debra M. Geno, Claude Deschamps, Aminah Jatoi, Jeff A Sloan, Yvonne Romero

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Background Patients with esophageal carcinoma (EC) report deficits in quality of life (QOL), depending on the extent of malignant disease and the goals of treatment at the time of QOL measurement. Aims To quantify the association of marital status and changes in QOL over time in patients with EC and patients with Barrett's esophagus (BE).Methods Eligible patients in the Mayo Clinic Esophageal Adenocarcinoma and Barrett's Esophagus Registry completed QOL assessments at baseline and approximately 1 year later. QOL was determined with a ten-point linear analog self-assessment scale evaluating overall QOL and 12 subscales. Results Overall, 489 BE patients and 212 EC patients were evaluated. Married EC patients reported higher baseline QOL in legal concerns (8.1 vs. 7.1; p = .04) and friendand family support (9.3 vs. 8.4; p = .02) than single EC patients. Over time, married EC patients had a decrease in pain frequency QOL compared to single EC patients (-0.9 vs. +0.6; p = .02), with other QOL measures being stable. Married BE patients showed higher social activity QOL at baseline than single BE patients (7.5 vs. 6.9; p = .02); QOL was stable over time between the marital status groups. Conclusions Minor, but statistically significant, changes were reported regarding QOL in two categories at baseline and over time among married and single patients with EC. Minor differences may be present between married and single EC patients regarding spiritual QOL at baseline and in overall physical well-being QOL at baseline and over time, although these differences did not reach statistical significance.

Original languageEnglish (US)
Pages (from-to)2860-2868
Number of pages9
JournalDigestive Diseases and Sciences
Volume55
Issue number10
DOIs
StatePublished - Oct 2010

Fingerprint

Barrett Esophagus
Marital Status
Esophageal Neoplasms
Registries
Quality of Life
Carcinoma
Adenocarcinoma Of Esophagus

Keywords

  • Barrett's esophagus
  • Esophageal neoplasms
  • Marital status
  • Quality of life

ASJC Scopus subject areas

  • Gastroenterology
  • Physiology

Cite this

Marital status and quality of life in patients with esophageal cancer or Barrett's Esophagus : The Mayo Clinic Esophageal Adenocarcinoma and Barrett's Esophagus registry study. / Miller, Robert C.; Atherton, Pamela J.; Kabat, Brian F.; Fredericksen, Mary B.; Geno, Debra M.; Deschamps, Claude; Jatoi, Aminah; Sloan, Jeff A; Romero, Yvonne.

In: Digestive Diseases and Sciences, Vol. 55, No. 10, 10.2010, p. 2860-2868.

Research output: Contribution to journalArticle

Miller, Robert C. ; Atherton, Pamela J. ; Kabat, Brian F. ; Fredericksen, Mary B. ; Geno, Debra M. ; Deschamps, Claude ; Jatoi, Aminah ; Sloan, Jeff A ; Romero, Yvonne. / Marital status and quality of life in patients with esophageal cancer or Barrett's Esophagus : The Mayo Clinic Esophageal Adenocarcinoma and Barrett's Esophagus registry study. In: Digestive Diseases and Sciences. 2010 ; Vol. 55, No. 10. pp. 2860-2868.
@article{decc051cf6a344409013d30107f0761a,
title = "Marital status and quality of life in patients with esophageal cancer or Barrett's Esophagus: The Mayo Clinic Esophageal Adenocarcinoma and Barrett's Esophagus registry study",
abstract = "Background Patients with esophageal carcinoma (EC) report deficits in quality of life (QOL), depending on the extent of malignant disease and the goals of treatment at the time of QOL measurement. Aims To quantify the association of marital status and changes in QOL over time in patients with EC and patients with Barrett's esophagus (BE).Methods Eligible patients in the Mayo Clinic Esophageal Adenocarcinoma and Barrett's Esophagus Registry completed QOL assessments at baseline and approximately 1 year later. QOL was determined with a ten-point linear analog self-assessment scale evaluating overall QOL and 12 subscales. Results Overall, 489 BE patients and 212 EC patients were evaluated. Married EC patients reported higher baseline QOL in legal concerns (8.1 vs. 7.1; p = .04) and friendand family support (9.3 vs. 8.4; p = .02) than single EC patients. Over time, married EC patients had a decrease in pain frequency QOL compared to single EC patients (-0.9 vs. +0.6; p = .02), with other QOL measures being stable. Married BE patients showed higher social activity QOL at baseline than single BE patients (7.5 vs. 6.9; p = .02); QOL was stable over time between the marital status groups. Conclusions Minor, but statistically significant, changes were reported regarding QOL in two categories at baseline and over time among married and single patients with EC. Minor differences may be present between married and single EC patients regarding spiritual QOL at baseline and in overall physical well-being QOL at baseline and over time, although these differences did not reach statistical significance.",
keywords = "Barrett's esophagus, Esophageal neoplasms, Marital status, Quality of life",
author = "Miller, {Robert C.} and Atherton, {Pamela J.} and Kabat, {Brian F.} and Fredericksen, {Mary B.} and Geno, {Debra M.} and Claude Deschamps and Aminah Jatoi and Sloan, {Jeff A} and Yvonne Romero",
year = "2010",
month = "10",
doi = "10.1007/s10620-009-1100-1",
language = "English (US)",
volume = "55",
pages = "2860--2868",
journal = "Digestive Diseases and Sciences",
issn = "0163-2116",
publisher = "Springer New York",
number = "10",

}

TY - JOUR

T1 - Marital status and quality of life in patients with esophageal cancer or Barrett's Esophagus

T2 - The Mayo Clinic Esophageal Adenocarcinoma and Barrett's Esophagus registry study

AU - Miller, Robert C.

AU - Atherton, Pamela J.

AU - Kabat, Brian F.

AU - Fredericksen, Mary B.

AU - Geno, Debra M.

AU - Deschamps, Claude

AU - Jatoi, Aminah

AU - Sloan, Jeff A

AU - Romero, Yvonne

PY - 2010/10

Y1 - 2010/10

N2 - Background Patients with esophageal carcinoma (EC) report deficits in quality of life (QOL), depending on the extent of malignant disease and the goals of treatment at the time of QOL measurement. Aims To quantify the association of marital status and changes in QOL over time in patients with EC and patients with Barrett's esophagus (BE).Methods Eligible patients in the Mayo Clinic Esophageal Adenocarcinoma and Barrett's Esophagus Registry completed QOL assessments at baseline and approximately 1 year later. QOL was determined with a ten-point linear analog self-assessment scale evaluating overall QOL and 12 subscales. Results Overall, 489 BE patients and 212 EC patients were evaluated. Married EC patients reported higher baseline QOL in legal concerns (8.1 vs. 7.1; p = .04) and friendand family support (9.3 vs. 8.4; p = .02) than single EC patients. Over time, married EC patients had a decrease in pain frequency QOL compared to single EC patients (-0.9 vs. +0.6; p = .02), with other QOL measures being stable. Married BE patients showed higher social activity QOL at baseline than single BE patients (7.5 vs. 6.9; p = .02); QOL was stable over time between the marital status groups. Conclusions Minor, but statistically significant, changes were reported regarding QOL in two categories at baseline and over time among married and single patients with EC. Minor differences may be present between married and single EC patients regarding spiritual QOL at baseline and in overall physical well-being QOL at baseline and over time, although these differences did not reach statistical significance.

AB - Background Patients with esophageal carcinoma (EC) report deficits in quality of life (QOL), depending on the extent of malignant disease and the goals of treatment at the time of QOL measurement. Aims To quantify the association of marital status and changes in QOL over time in patients with EC and patients with Barrett's esophagus (BE).Methods Eligible patients in the Mayo Clinic Esophageal Adenocarcinoma and Barrett's Esophagus Registry completed QOL assessments at baseline and approximately 1 year later. QOL was determined with a ten-point linear analog self-assessment scale evaluating overall QOL and 12 subscales. Results Overall, 489 BE patients and 212 EC patients were evaluated. Married EC patients reported higher baseline QOL in legal concerns (8.1 vs. 7.1; p = .04) and friendand family support (9.3 vs. 8.4; p = .02) than single EC patients. Over time, married EC patients had a decrease in pain frequency QOL compared to single EC patients (-0.9 vs. +0.6; p = .02), with other QOL measures being stable. Married BE patients showed higher social activity QOL at baseline than single BE patients (7.5 vs. 6.9; p = .02); QOL was stable over time between the marital status groups. Conclusions Minor, but statistically significant, changes were reported regarding QOL in two categories at baseline and over time among married and single patients with EC. Minor differences may be present between married and single EC patients regarding spiritual QOL at baseline and in overall physical well-being QOL at baseline and over time, although these differences did not reach statistical significance.

KW - Barrett's esophagus

KW - Esophageal neoplasms

KW - Marital status

KW - Quality of life

UR - http://www.scopus.com/inward/record.url?scp=77957891090&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77957891090&partnerID=8YFLogxK

U2 - 10.1007/s10620-009-1100-1

DO - 10.1007/s10620-009-1100-1

M3 - Article

C2 - 20094784

AN - SCOPUS:77957891090

VL - 55

SP - 2860

EP - 2868

JO - Digestive Diseases and Sciences

JF - Digestive Diseases and Sciences

SN - 0163-2116

IS - 10

ER -