Mapping and ablation of electrical rotor and focal sources for atrial fibrillation: A patient-tailored mechanistic approach

Junaid A.B. Zaman; Siva K. Mulpuru; David E. Krummen; Sanjiv M. Narayan

doi:10.1002/9781118658369.ch18

Mapping and ablation of electrical rotor and focal sources for atrial fibrillation: A patient-tailored mechanistic approach

Junaid A.B. Zaman, Siva K. Mulpuru, David E. Krummen, Sanjiv M. Narayan

Cardiovascular Diseases

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

This chapter illustrates electrical rotors in human atrial fibrillation (AF) and differences from atrial flutter on focal impulse and rotor mapping (FIRM) mapping. It displays the clinical characteristics of the patient group. Persistent AF was present in 81% of the FIRM-guided group, and in 66% of the FIRM-blinded group.It presents the nomenclature of FIRM maps, in which the left atrium is opened at its "equator" and the right atrium is opened along a meridian. Mapping analyzes contact electrograms, which are the reference standard for signal fidelity, using recently reported human rate-response properties of atrial repolarization and regional conduction. In FIRM-guided subjects, ablation commenced with the elimination of AF rotors or focal sources using various radiofrequency sources. CONFIRM and recent confirmatory multicenter studies of FIRM were not randomized, although subjects were enrolled and treated prospectively for prespecified end points.

Original language	English (US)
Title of host publication	Practical Guide to Catheter Ablation of Atrial Fibrillation
Subtitle of host publication	Second Edition
Publisher	Wiley-Blackwell
Pages	271-282
Number of pages	12
ISBN (Electronic)	9781118658369
ISBN (Print)	9781118658505
DOIs	https://doi.org/10.1002/9781118658369.ch18
State	Published - Dec 5 2015

Keywords

Atrial fibrillation
Electrical rotors
Electrogram
FIRM ablation
FIRM mapping

ASJC Scopus subject areas

General Medicine

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10.1002/9781118658369.ch18

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Mapping and ablation of electrical rotor and focal sources for atrial fibrillation: A patient-tailored mechanistic approach. / Zaman, Junaid A.B.; Mulpuru, Siva K.; Krummen, David E. et al.
Practical Guide to Catheter Ablation of Atrial Fibrillation: Second Edition. Wiley-Blackwell, 2015. p. 271-282.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

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abstract = "This chapter illustrates electrical rotors in human atrial fibrillation (AF) and differences from atrial flutter on focal impulse and rotor mapping (FIRM) mapping. It displays the clinical characteristics of the patient group. Persistent AF was present in 81% of the FIRM-guided group, and in 66% of the FIRM-blinded group.It presents the nomenclature of FIRM maps, in which the left atrium is opened at its {"}equator{"} and the right atrium is opened along a meridian. Mapping analyzes contact electrograms, which are the reference standard for signal fidelity, using recently reported human rate-response properties of atrial repolarization and regional conduction. In FIRM-guided subjects, ablation commenced with the elimination of AF rotors or focal sources using various radiofrequency sources. CONFIRM and recent confirmatory multicenter studies of FIRM were not randomized, although subjects were enrolled and treated prospectively for prespecified end points.",

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AU - Zaman, Junaid A.B.

AU - Mulpuru, Siva K.

AU - Krummen, David E.

AU - Narayan, Sanjiv M.

PY - 2015/12/5

Y1 - 2015/12/5

N2 - This chapter illustrates electrical rotors in human atrial fibrillation (AF) and differences from atrial flutter on focal impulse and rotor mapping (FIRM) mapping. It displays the clinical characteristics of the patient group. Persistent AF was present in 81% of the FIRM-guided group, and in 66% of the FIRM-blinded group.It presents the nomenclature of FIRM maps, in which the left atrium is opened at its "equator" and the right atrium is opened along a meridian. Mapping analyzes contact electrograms, which are the reference standard for signal fidelity, using recently reported human rate-response properties of atrial repolarization and regional conduction. In FIRM-guided subjects, ablation commenced with the elimination of AF rotors or focal sources using various radiofrequency sources. CONFIRM and recent confirmatory multicenter studies of FIRM were not randomized, although subjects were enrolled and treated prospectively for prespecified end points.

AB - This chapter illustrates electrical rotors in human atrial fibrillation (AF) and differences from atrial flutter on focal impulse and rotor mapping (FIRM) mapping. It displays the clinical characteristics of the patient group. Persistent AF was present in 81% of the FIRM-guided group, and in 66% of the FIRM-blinded group.It presents the nomenclature of FIRM maps, in which the left atrium is opened at its "equator" and the right atrium is opened along a meridian. Mapping analyzes contact electrograms, which are the reference standard for signal fidelity, using recently reported human rate-response properties of atrial repolarization and regional conduction. In FIRM-guided subjects, ablation commenced with the elimination of AF rotors or focal sources using various radiofrequency sources. CONFIRM and recent confirmatory multicenter studies of FIRM were not randomized, although subjects were enrolled and treated prospectively for prespecified end points.

KW - Atrial fibrillation

KW - Electrical rotors

KW - Electrogram

KW - FIRM ablation

KW - FIRM mapping

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PB - Wiley-Blackwell

ER -

Mapping and ablation of electrical rotor and focal sources for atrial fibrillation: A patient-tailored mechanistic approach

Abstract

Keywords

ASJC Scopus subject areas

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