Manifestations of systemic lupus erythematosus in female patients with polysomy X

Possible roles of chromosome X

Taro Iwamoto, Masanori Fujimoto, Kei Ikeda, Aiko Saku, Sohei Makita, Shunsuke Furuta, Timothy B. Niewold, Hiroshi Nakajima

Research output: Contribution to journalArticle

Abstract

Clinical manifestations of systemic lupus erythematosus (SLE) in female patients with polysomy X have been less characterized as compared to those in male patients. Here, we describe a 28-year-old woman with trisomy X (47,XXX) who developed SLE. She had polyarthritis, hemolytic anemia, and was positive for anti-nuclear and anti-dsDNA antibodies. We discuss the common SLE manifestations with female polysomy X and the possible link between the development of SLE and the presence of extra X-chromosomes.

Original languageEnglish (US)
Pages (from-to)1-3
Number of pages3
JournalModern Rheumatology
DOIs
StateAccepted/In press - Jul 11 2016

Fingerprint

X Chromosome
Systemic Lupus Erythematosus
Hemolytic Anemia
Arthritis
Anti-Idiotypic Antibodies

Keywords

  • Arthritis
  • Female
  • Hemolytic anemia
  • Systemic lupus erythematosus
  • Trisomy X

ASJC Scopus subject areas

  • Rheumatology

Cite this

Iwamoto, T., Fujimoto, M., Ikeda, K., Saku, A., Makita, S., Furuta, S., ... Nakajima, H. (Accepted/In press). Manifestations of systemic lupus erythematosus in female patients with polysomy X: Possible roles of chromosome X. Modern Rheumatology, 1-3. https://doi.org/10.1080/14397595.2016.1205800

Manifestations of systemic lupus erythematosus in female patients with polysomy X : Possible roles of chromosome X. / Iwamoto, Taro; Fujimoto, Masanori; Ikeda, Kei; Saku, Aiko; Makita, Sohei; Furuta, Shunsuke; Niewold, Timothy B.; Nakajima, Hiroshi.

In: Modern Rheumatology, 11.07.2016, p. 1-3.

Research output: Contribution to journalArticle

Iwamoto, Taro ; Fujimoto, Masanori ; Ikeda, Kei ; Saku, Aiko ; Makita, Sohei ; Furuta, Shunsuke ; Niewold, Timothy B. ; Nakajima, Hiroshi. / Manifestations of systemic lupus erythematosus in female patients with polysomy X : Possible roles of chromosome X. In: Modern Rheumatology. 2016 ; pp. 1-3.
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