Abstract
The 3 major and potentially fatal complications of cirrhosis of the liver result from portal hypertension and include variceal bleeding, ascites, and encephalopathy. The cause of other complications, eg, thyroid dysfunction and hepatopulmonary syndrome, is uncertain. Several recent advances have occurred in the treatment of varices. However, treatment of ascites is still primarily confined to achieving a negative sodium balance, and therapy for encephalopathy centers on the use of lactulose. Although effective therapy may be available for most complications of cirrhosis, a major complication indicates a poor longterm prognosis. Liver transplantation the only effective long-term treatment of complications due to cirrhosis.
Original language | English (US) |
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Pages (from-to) | 501-509 |
Number of pages | 9 |
Journal | Mayo Clinic Proceedings |
Volume | 75 |
Issue number | 5 |
State | Published - 2000 |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
Managing the complications of cirrhosis. / Narayanan Menon, K. V.; Kamath, Patrick Sequeira.
In: Mayo Clinic Proceedings, Vol. 75, No. 5, 2000, p. 501-509.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Managing the complications of cirrhosis
AU - Narayanan Menon, K. V.
AU - Kamath, Patrick Sequeira
PY - 2000
Y1 - 2000
N2 - The 3 major and potentially fatal complications of cirrhosis of the liver result from portal hypertension and include variceal bleeding, ascites, and encephalopathy. The cause of other complications, eg, thyroid dysfunction and hepatopulmonary syndrome, is uncertain. Several recent advances have occurred in the treatment of varices. However, treatment of ascites is still primarily confined to achieving a negative sodium balance, and therapy for encephalopathy centers on the use of lactulose. Although effective therapy may be available for most complications of cirrhosis, a major complication indicates a poor longterm prognosis. Liver transplantation the only effective long-term treatment of complications due to cirrhosis.
AB - The 3 major and potentially fatal complications of cirrhosis of the liver result from portal hypertension and include variceal bleeding, ascites, and encephalopathy. The cause of other complications, eg, thyroid dysfunction and hepatopulmonary syndrome, is uncertain. Several recent advances have occurred in the treatment of varices. However, treatment of ascites is still primarily confined to achieving a negative sodium balance, and therapy for encephalopathy centers on the use of lactulose. Although effective therapy may be available for most complications of cirrhosis, a major complication indicates a poor longterm prognosis. Liver transplantation the only effective long-term treatment of complications due to cirrhosis.
UR - http://www.scopus.com/inward/record.url?scp=0034063653&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034063653&partnerID=8YFLogxK
M3 - Article
C2 - 10807079
AN - SCOPUS:0034063653
VL - 75
SP - 501
EP - 509
JO - Mayo Clinic Proceedings
JF - Mayo Clinic Proceedings
SN - 0025-6196
IS - 5
ER -