TY - JOUR
T1 - Managing the complications of cirrhosis
AU - Narayanan Menon, K. V.
AU - Kamath, Patrick S.
N1 - Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2000
Y1 - 2000
N2 - The 3 major and potentially fatal complications of cirrhosis of the liver result from portal hypertension and include variceal bleeding, ascites, and encephalopathy. The cause of other complications, eg, thyroid dysfunction and hepatopulmonary syndrome, is uncertain. Several recent advances have occurred in the treatment of varices. However, treatment of ascites is still primarily confined to achieving a negative sodium balance, and therapy for encephalopathy centers on the use of lactulose. Although effective therapy may be available for most complications of cirrhosis, a major complication indicates a poor longterm prognosis. Liver transplantation the only effective long-term treatment of complications due to cirrhosis.
AB - The 3 major and potentially fatal complications of cirrhosis of the liver result from portal hypertension and include variceal bleeding, ascites, and encephalopathy. The cause of other complications, eg, thyroid dysfunction and hepatopulmonary syndrome, is uncertain. Several recent advances have occurred in the treatment of varices. However, treatment of ascites is still primarily confined to achieving a negative sodium balance, and therapy for encephalopathy centers on the use of lactulose. Although effective therapy may be available for most complications of cirrhosis, a major complication indicates a poor longterm prognosis. Liver transplantation the only effective long-term treatment of complications due to cirrhosis.
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U2 - 10.1016/s0025-6196(11)64219-5
DO - 10.1016/s0025-6196(11)64219-5
M3 - Review article
C2 - 10807079
AN - SCOPUS:0034063653
SN - 0025-6196
VL - 75
SP - 501
EP - 509
JO - Mayo Clinic Proceedings
JF - Mayo Clinic Proceedings
IS - 5
ER -