TY - JOUR
T1 - Managing expectational language
T2 - Translational genetic professionals consider the clinical potential of next-generation sequencing technologies
AU - Koay, Pei P.
AU - Sharp, Richard R.
N1 - Funding Information:
This work was supported by the National Human Genome Research Institute [NHGRI-ELSI R01HG004500 and P50HG003390]. The authors would like to thank Michelle McGowan and Jenni-fer Fishman for their helpful comments on earlier versions of this article. We also thank the editors of New Genetics and Society and three anonymous reviewers for comments that improved this paper. We would also like to acknowledge the work of the research team, but especially Janelle Highland and MaryBeth Mercer.
PY - 2014/4/3
Y1 - 2014/4/3
N2 - Clinical genetic professionals are used to being flooded by claims about the seemingly endless potential and promise of next-generation sequencing (NGS) in medicine today. This paper is about managing expectations in translational medicine. From 2009 to 2011, we conducted focus groups with genetic and allied professionals concerned with genomics in the clinic to examine their attitudes and perspectives of genetic and genomic tools in this environment. In this paper, we examine and explore some of their discussions, specifically related to NGS and whole genome sequencing tests and their introduction as normal clinical tools. Informed by sociology of expectations (SE), we discuss expectational language in the arena of translational medicine. Through SE, illuminated are some barriers and strategies used by professionals to manage expectations. Further, our work suggests the importance of SE and more nuanced study to understand the discursive realm of translational genomic medicine.
AB - Clinical genetic professionals are used to being flooded by claims about the seemingly endless potential and promise of next-generation sequencing (NGS) in medicine today. This paper is about managing expectations in translational medicine. From 2009 to 2011, we conducted focus groups with genetic and allied professionals concerned with genomics in the clinic to examine their attitudes and perspectives of genetic and genomic tools in this environment. In this paper, we examine and explore some of their discussions, specifically related to NGS and whole genome sequencing tests and their introduction as normal clinical tools. Informed by sociology of expectations (SE), we discuss expectational language in the arena of translational medicine. Through SE, illuminated are some barriers and strategies used by professionals to manage expectations. Further, our work suggests the importance of SE and more nuanced study to understand the discursive realm of translational genomic medicine.
KW - Clinical genomics
KW - Expectations
KW - New medical technologies
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U2 - 10.1080/14636778.2014.910448
DO - 10.1080/14636778.2014.910448
M3 - Article
AN - SCOPUS:84901022305
SN - 1463-6778
VL - 33
SP - 126
EP - 148
JO - New Genetics and Society
JF - New Genetics and Society
IS - 2
ER -