Management of Stage IIIA (N2) Non–Small Cell Lung Cancer

Erin A. Gillaspie, Dennis A Wigle

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

There is no consensus as to the optimal management of IIIA (N2) non–small cell lung cancer, nor for the role of surgery in treating this disease stage. Clinical trial evidence struggles to keep up with technology advancement and the evolution of expert opinion. Despite advances in chemotherapeutic regimens, methods of delivery for radiation, and less invasive surgical techniques, survival for patients with stage IIIA-N2 malignancies remains poor. Further developments in both will stimulate and maintain controversy in the field for years to come.

Original languageEnglish (US)
Pages (from-to)271-285
Number of pages15
JournalThoracic Surgery Clinics
Volume26
Issue number3
DOIs
StatePublished - Aug 1 2016

Fingerprint

Expert Testimony
Non-Small Cell Lung Carcinoma
Clinical Trials
Radiation
Technology
Survival
Neoplasms

Keywords

  • Adjuvant
  • N2
  • Neoadjuvant
  • Non–small cell lung cancer
  • PORT
  • Stage IIIA
  • Surgery

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine

Cite this

Management of Stage IIIA (N2) Non–Small Cell Lung Cancer. / Gillaspie, Erin A.; Wigle, Dennis A.

In: Thoracic Surgery Clinics, Vol. 26, No. 3, 01.08.2016, p. 271-285.

Research output: Contribution to journalReview article

@article{da7da40ba9284712a712a9b9c053b50f,
title = "Management of Stage IIIA (N2) Non–Small Cell Lung Cancer",
abstract = "There is no consensus as to the optimal management of IIIA (N2) non–small cell lung cancer, nor for the role of surgery in treating this disease stage. Clinical trial evidence struggles to keep up with technology advancement and the evolution of expert opinion. Despite advances in chemotherapeutic regimens, methods of delivery for radiation, and less invasive surgical techniques, survival for patients with stage IIIA-N2 malignancies remains poor. Further developments in both will stimulate and maintain controversy in the field for years to come.",
keywords = "Adjuvant, N2, Neoadjuvant, Non–small cell lung cancer, PORT, Stage IIIA, Surgery",
author = "Gillaspie, {Erin A.} and Wigle, {Dennis A}",
year = "2016",
month = "8",
day = "1",
doi = "10.1016/j.thorsurg.2016.04.001",
language = "English (US)",
volume = "26",
pages = "271--285",
journal = "Thoracic Surgery Clinics",
issn = "1547-4127",
publisher = "W.B. Saunders Ltd",
number = "3",

}

TY - JOUR

T1 - Management of Stage IIIA (N2) Non–Small Cell Lung Cancer

AU - Gillaspie, Erin A.

AU - Wigle, Dennis A

PY - 2016/8/1

Y1 - 2016/8/1

N2 - There is no consensus as to the optimal management of IIIA (N2) non–small cell lung cancer, nor for the role of surgery in treating this disease stage. Clinical trial evidence struggles to keep up with technology advancement and the evolution of expert opinion. Despite advances in chemotherapeutic regimens, methods of delivery for radiation, and less invasive surgical techniques, survival for patients with stage IIIA-N2 malignancies remains poor. Further developments in both will stimulate and maintain controversy in the field for years to come.

AB - There is no consensus as to the optimal management of IIIA (N2) non–small cell lung cancer, nor for the role of surgery in treating this disease stage. Clinical trial evidence struggles to keep up with technology advancement and the evolution of expert opinion. Despite advances in chemotherapeutic regimens, methods of delivery for radiation, and less invasive surgical techniques, survival for patients with stage IIIA-N2 malignancies remains poor. Further developments in both will stimulate and maintain controversy in the field for years to come.

KW - Adjuvant

KW - N2

KW - Neoadjuvant

KW - Non–small cell lung cancer

KW - PORT

KW - Stage IIIA

KW - Surgery

UR - http://www.scopus.com/inward/record.url?scp=84990866185&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84990866185&partnerID=8YFLogxK

U2 - 10.1016/j.thorsurg.2016.04.001

DO - 10.1016/j.thorsurg.2016.04.001

M3 - Review article

C2 - 27427522

AN - SCOPUS:84990866185

VL - 26

SP - 271

EP - 285

JO - Thoracic Surgery Clinics

JF - Thoracic Surgery Clinics

SN - 1547-4127

IS - 3

ER -