Management of opioid-induced constipation

David Prichard, Christine Norton, Adil Eddie Bharucha

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Up to 40% of patients taking opioids develop constipation. Opioid-induced constipation (OIC) may limit the adequate dosing of opioids for pain relief and reduce quality of life. Health professionals must therefore inquire about bowel function in patients receiving opioids. The management of OIC includes carefully re-evaluating the necessity, type and dose of opioids at each visit. Lifestyle modification and alteration of aggravating factors, the use of simple laxatives and, when essential, the addition of newer laxatives or opioid antagonists (naloxone, naloxegol or methylnaltrexone) can be used to treat OIC. This review discusses the recent literature regarding the management of OIC and provides a rational approach to assessing and managing constipation in individuals receiving opioids.

Original languageEnglish (US)
Pages (from-to)S4-S11
JournalBritish Journal of Nursing
Volume25
Issue number10
DOIs
StatePublished - 2016

Fingerprint

Constipation
Opioid Analgesics
Laxatives
Narcotic Antagonists
Life Style
Quality of Life
Pain
Health

Keywords

  • Chronic pain
  • Constipation
  • Laxatives
  • Methylnaltrexone
  • Naloxegol
  • Naloxone
  • Opioids

ASJC Scopus subject areas

  • Nursing(all)
  • Medicine(all)

Cite this

Management of opioid-induced constipation. / Prichard, David; Norton, Christine; Bharucha, Adil Eddie.

In: British Journal of Nursing, Vol. 25, No. 10, 2016, p. S4-S11.

Research output: Contribution to journalArticle

Prichard, David ; Norton, Christine ; Bharucha, Adil Eddie. / Management of opioid-induced constipation. In: British Journal of Nursing. 2016 ; Vol. 25, No. 10. pp. S4-S11.
@article{dc74f5cae74a4856b70ab8b434b453c4,
title = "Management of opioid-induced constipation",
abstract = "Up to 40{\%} of patients taking opioids develop constipation. Opioid-induced constipation (OIC) may limit the adequate dosing of opioids for pain relief and reduce quality of life. Health professionals must therefore inquire about bowel function in patients receiving opioids. The management of OIC includes carefully re-evaluating the necessity, type and dose of opioids at each visit. Lifestyle modification and alteration of aggravating factors, the use of simple laxatives and, when essential, the addition of newer laxatives or opioid antagonists (naloxone, naloxegol or methylnaltrexone) can be used to treat OIC. This review discusses the recent literature regarding the management of OIC and provides a rational approach to assessing and managing constipation in individuals receiving opioids.",
keywords = "Chronic pain, Constipation, Laxatives, Methylnaltrexone, Naloxegol, Naloxone, Opioids",
author = "David Prichard and Christine Norton and Bharucha, {Adil Eddie}",
year = "2016",
doi = "10.12968/bjon.2016.25.10.S4",
language = "English (US)",
volume = "25",
pages = "S4--S11",
journal = "British Journal of Nursing",
issn = "0966-0461",
publisher = "MA Healthcare Ltd",
number = "10",

}

TY - JOUR

T1 - Management of opioid-induced constipation

AU - Prichard, David

AU - Norton, Christine

AU - Bharucha, Adil Eddie

PY - 2016

Y1 - 2016

N2 - Up to 40% of patients taking opioids develop constipation. Opioid-induced constipation (OIC) may limit the adequate dosing of opioids for pain relief and reduce quality of life. Health professionals must therefore inquire about bowel function in patients receiving opioids. The management of OIC includes carefully re-evaluating the necessity, type and dose of opioids at each visit. Lifestyle modification and alteration of aggravating factors, the use of simple laxatives and, when essential, the addition of newer laxatives or opioid antagonists (naloxone, naloxegol or methylnaltrexone) can be used to treat OIC. This review discusses the recent literature regarding the management of OIC and provides a rational approach to assessing and managing constipation in individuals receiving opioids.

AB - Up to 40% of patients taking opioids develop constipation. Opioid-induced constipation (OIC) may limit the adequate dosing of opioids for pain relief and reduce quality of life. Health professionals must therefore inquire about bowel function in patients receiving opioids. The management of OIC includes carefully re-evaluating the necessity, type and dose of opioids at each visit. Lifestyle modification and alteration of aggravating factors, the use of simple laxatives and, when essential, the addition of newer laxatives or opioid antagonists (naloxone, naloxegol or methylnaltrexone) can be used to treat OIC. This review discusses the recent literature regarding the management of OIC and provides a rational approach to assessing and managing constipation in individuals receiving opioids.

KW - Chronic pain

KW - Constipation

KW - Laxatives

KW - Methylnaltrexone

KW - Naloxegol

KW - Naloxone

KW - Opioids

UR - http://www.scopus.com/inward/record.url?scp=84971425258&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84971425258&partnerID=8YFLogxK

U2 - 10.12968/bjon.2016.25.10.S4

DO - 10.12968/bjon.2016.25.10.S4

M3 - Article

C2 - 27231750

AN - SCOPUS:84971425258

VL - 25

SP - S4-S11

JO - British Journal of Nursing

JF - British Journal of Nursing

SN - 0966-0461

IS - 10

ER -