Management of metastatic gastrointestinal stromal tumor by multiple surgical interventions including pancreatoduodenectomy, liver resection and two liver transplants: Worth the effort?

M. Dougherty, H. Bonatti, R. C. Dickson, J. Aranda-Michel, R. Hinder, J. Nguyen, J. Steers, Christopher B. Hughes

Research output: Contribution to journalArticle


Background: Gastrointestinal stromal tumor (GIST) is a rare malignant disease which originates from the pacemaker cells of the gastrointestinal tract and in the case of metastatic spread usually has a poor prognosis. Methods: We report a case of a woman who underwent multiple surgical procedures including a pancreatic resection and two liver transplants and in addition received Gleevec, somatostatin and the new experimental compound Sunitinib. Results: With this intensive approach she survived more than 12 years after being first diagnosed with GIST. Conclusions: In selected cases patients with metastatic GIST may benefit from such an aggressive approach.

Original languageEnglish (US)
Pages (from-to)189-191
Number of pages3
JournalEuropean Surgery - Acta Chirurgica Austriaca
Issue number3
StatePublished - Jul 31 2007



  • GIST
  • Gleevec
  • Liver transplant

ASJC Scopus subject areas

  • Surgery

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