Abstract
Some melanomas develop a striking avidity for lymphatic spread. In spite of multiple recurrences, patients can remain years without visceral metastasis. There is clearly a biologic reason for this lymphotrophic pattern of growth and dissemination, which we have yet to uncover. In-transit metastases have widely diverse clinical presentations and can be a stubborn disease to cure. As a result, a host of treatments exist that should be tailored to the individual patient.
Original language | English (US) |
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Pages (from-to) | 187-199 |
Number of pages | 13 |
Journal | Journal of Surgical Oncology |
Volume | 119 |
Issue number | 2 |
DOIs | |
State | Published - Feb 1 2019 |
Keywords
- diphenylcyclopropenone
- in transit
- intralesional therapy
- limb perfusion
- melanoma, stage III
- talimogene laherparepvec
ASJC Scopus subject areas
- Surgery
- Oncology