Management of intracerebral hemorrhage in a large metropolitan population

J. Broderick, Thomas G Brott, T. Tomsick, J. Tew, J. Duldner, G. Huster, R. H. Patterson, R. R. Smith, W. R. Selma

Research output: Contribution to journalArticle

107 Citations (Scopus)

Abstract

THE MANAGEMENT OF all patients with spontaneous, nonaneurysmal intracerebral hemorrhages that occurred in the 1.26 million population of Greater Cincinnati during 1988 was reviewed. Of the 188 patients with intracerebral hemorrhage, 26 had operative removal of their intracerebral hemorrhage, and 8 had removal of their intracerebral hemorrhage and an arteriovenous malformation. In 15 of the 34 patients, the operation was performed within 12 hours of onset. The operative removal of parenchymal hemorrhages was performed in 29% of cerebellar, 24% of lobar, 13% of deep, and 10% of pontine hemorrhages. Admission Glasgow Coma Scale scores were similar for operated and nonoperated patients (11 ± 3 versus 11 ± 3), but operated patients were significantly younger (58 ± 17 versus 72 ± 15 yr), were more likely to have a lobar hemorrhage (64 versus 43%) or a cerebellar hemorrhage (29 versus 7%), and had larger parenchymal hemorrhages (50 ± 31 versus 37 ± 38 ml). Operated patients had a borderline lower 30-day mortality (25%) than nonoperated patients (46%), but the overall morbidity and mortality for the two groups did not differ significantly. Patients undergoing an early operation were more critically ill preoperatively and had a greater 30-day mortality (45%) than did those patients undergoing a late operation (12%). Half of the 43% mortality for all hospitalized cases occurred during the first 2 days after onset, and two-thirds occurred during the first 4 days. Only 12% of all patients had a minor handicap or better at 30 days. Neurosurgeons in our community performed operative removal of parenchymal hemorrhage in nearly one fifth of all patients with intracerebral hemorrhage. Younger patients with larger lobar or cerebellar hemorrhages were most likely to undergo an operation. The very high and very early mortality associated with the management of intracerebral hemorrhage in our community during 1988 suggests the need for innovative, ultraearly treatment strategies.

Original languageEnglish (US)
Pages (from-to)882-887
Number of pages6
JournalNeurosurgery
Volume34
Issue number5
StatePublished - 1994
Externally publishedYes

Fingerprint

Cerebral Hemorrhage
Population
Hemorrhage
Mortality
Glasgow Coma Scale
Arteriovenous Malformations
Critical Illness
Morbidity

Keywords

  • Intracerebral hemorrhage
  • Operation
  • Outcome
  • Treatment

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Broderick, J., Brott, T. G., Tomsick, T., Tew, J., Duldner, J., Huster, G., ... Selma, W. R. (1994). Management of intracerebral hemorrhage in a large metropolitan population. Neurosurgery, 34(5), 882-887.

Management of intracerebral hemorrhage in a large metropolitan population. / Broderick, J.; Brott, Thomas G; Tomsick, T.; Tew, J.; Duldner, J.; Huster, G.; Patterson, R. H.; Smith, R. R.; Selma, W. R.

In: Neurosurgery, Vol. 34, No. 5, 1994, p. 882-887.

Research output: Contribution to journalArticle

Broderick, J, Brott, TG, Tomsick, T, Tew, J, Duldner, J, Huster, G, Patterson, RH, Smith, RR & Selma, WR 1994, 'Management of intracerebral hemorrhage in a large metropolitan population', Neurosurgery, vol. 34, no. 5, pp. 882-887.
Broderick J, Brott TG, Tomsick T, Tew J, Duldner J, Huster G et al. Management of intracerebral hemorrhage in a large metropolitan population. Neurosurgery. 1994;34(5):882-887.
Broderick, J. ; Brott, Thomas G ; Tomsick, T. ; Tew, J. ; Duldner, J. ; Huster, G. ; Patterson, R. H. ; Smith, R. R. ; Selma, W. R. / Management of intracerebral hemorrhage in a large metropolitan population. In: Neurosurgery. 1994 ; Vol. 34, No. 5. pp. 882-887.
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