TY - JOUR
T1 - Management of hyperhidrosis
AU - Stashak, Anna Bianca
AU - Brewer, Jerry D.
N1 - Publisher Copyright:
© 2014 Stashak and Brewer.
PY - 2014/10/29
Y1 - 2014/10/29
N2 - Primary hyperhidrosis (HH), a condition of sweating in excess of thermoregulatory requirements, affects nearly 3% of the US population and carries significant emotional and psychosocial implications. Unlike secondary HH, primary HH is not associated with an identifiable underlying pathology. Our limited understanding of the precise pathophysiologic mechanism for HH makes its treatment particularly frustrating. However, a wide array of interventions for the treatment of HH have been implemented throughout the world. Herein, we discuss the most extensively studied therapeutic options for primary HH, including systemic oxybutynin, botulinum toxin injections, skin excision, liposuction–curettage, and sympathotomy/sympathectomy. We conclude with a discussion of possible future therapies for HH, including the applications of laser, microwave, and ultrasound technologies.
AB - Primary hyperhidrosis (HH), a condition of sweating in excess of thermoregulatory requirements, affects nearly 3% of the US population and carries significant emotional and psychosocial implications. Unlike secondary HH, primary HH is not associated with an identifiable underlying pathology. Our limited understanding of the precise pathophysiologic mechanism for HH makes its treatment particularly frustrating. However, a wide array of interventions for the treatment of HH have been implemented throughout the world. Herein, we discuss the most extensively studied therapeutic options for primary HH, including systemic oxybutynin, botulinum toxin injections, skin excision, liposuction–curettage, and sympathotomy/sympathectomy. We conclude with a discussion of possible future therapies for HH, including the applications of laser, microwave, and ultrasound technologies.
KW - Botulinum toxin
KW - Eccrine ducts
KW - Laser
KW - Primary hyperhidrosis
KW - Secondary hyperhidrosis
KW - Surgery
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U2 - 10.2147/CCID.S53119
DO - 10.2147/CCID.S53119
M3 - Review article
AN - SCOPUS:84908306439
SN - 1178-7015
VL - 7
SP - 285
EP - 299
JO - Clinical, Cosmetic and Investigational Dermatology
JF - Clinical, Cosmetic and Investigational Dermatology
ER -