TY - JOUR
T1 - Management of Antiplatelet Agents and Anticoagulants in Patients with Gastrointestinal Bleeding
AU - Abraham, Neena S.
N1 - Publisher Copyright:
© 2015 Elsevier Inc.
PY - 2015/7/1
Y1 - 2015/7/1
N2 - Antithrombotic drugs (anticoagulants, aspirin, and other antiplatelet agents) are used to treat cardiovascular disease and to prevent secondary thromboembolic events. These drugs are independently associated with an increased risk of gastrointestinal bleeding (GIB), and, when prescribed in combination, further increase the risk of adverse bleeding events. Clinical evidence to inform the choice of endoscopic hemostatic procedure, safe temporary drug cessation, and use of reversal agents is reviewed to optimize management following clinically significant GIB.
AB - Antithrombotic drugs (anticoagulants, aspirin, and other antiplatelet agents) are used to treat cardiovascular disease and to prevent secondary thromboembolic events. These drugs are independently associated with an increased risk of gastrointestinal bleeding (GIB), and, when prescribed in combination, further increase the risk of adverse bleeding events. Clinical evidence to inform the choice of endoscopic hemostatic procedure, safe temporary drug cessation, and use of reversal agents is reviewed to optimize management following clinically significant GIB.
KW - Adverse effects
KW - Gastrointestinal hemorrhage
KW - Lower gastrointestinal bleeding
KW - Novel oral anticoagulant
KW - Thienopyridine
KW - Upper gastrointestinal bleeding
UR - http://www.scopus.com/inward/record.url?scp=84937631852&partnerID=8YFLogxK
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U2 - 10.1016/j.giec.2015.02.002
DO - 10.1016/j.giec.2015.02.002
M3 - Review article
C2 - 26142031
AN - SCOPUS:84937631852
SN - 1052-5157
VL - 25
SP - 449
EP - 462
JO - Gastrointestinal Endoscopy Clinics of North America
JF - Gastrointestinal Endoscopy Clinics of North America
IS - 3
ER -