Male breast cancer: An 11 year review of 66 patients

Sue Anne McLachlan, Charles Erlichman, Fei Fei Liu, Naomi Miller, Melania Pintilie

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

A review was conducted of 66 men with carcinoma of the breast seen at this institution between 1981 and 1992. The results of the study suggest that there are many similarities between breast cancer in men and women. The most common clinical presentation was a lump in the breast. The majority of tumors were T1 or T2, and infiltrating ductal carcinoma was the predominant histological type. Axillary nodal status and histological grade were predictive of survival. The pattern of recurrence and survival rates were similar to those seen in women. Some differences, however, were evident. Tumors were centrally located in the majority of patients and there was a high frequency of nipple involvement. The hormone receptor positivity rate was high and the median age at presentation was older. In comparison to a previous report of the same disease from this institution 10 years ago, fewer patients underwent radical surgical procedures and more patients received adjuvant systemic therapy. These approaches are justified since there are many biological similarities between breast cancer in men and women.

Original languageEnglish (US)
Pages (from-to)225-230
Number of pages6
JournalBreast Cancer Research and Treatment
Volume40
Issue number3
DOIs
StatePublished - 1996

Fingerprint

Male Breast Neoplasms
Breast Neoplasms
Ductal Carcinoma
Nipples
Neoplasms
Breast
Survival Rate
Hormones
Recurrence
Survival
Therapeutics

Keywords

  • Breast cancer
  • Case series
  • Male

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

McLachlan, S. A., Erlichman, C., Liu, F. F., Miller, N., & Pintilie, M. (1996). Male breast cancer: An 11 year review of 66 patients. Breast Cancer Research and Treatment, 40(3), 225-230. https://doi.org/10.1007/BF01806810

Male breast cancer : An 11 year review of 66 patients. / McLachlan, Sue Anne; Erlichman, Charles; Liu, Fei Fei; Miller, Naomi; Pintilie, Melania.

In: Breast Cancer Research and Treatment, Vol. 40, No. 3, 1996, p. 225-230.

Research output: Contribution to journalArticle

McLachlan, SA, Erlichman, C, Liu, FF, Miller, N & Pintilie, M 1996, 'Male breast cancer: An 11 year review of 66 patients', Breast Cancer Research and Treatment, vol. 40, no. 3, pp. 225-230. https://doi.org/10.1007/BF01806810
McLachlan, Sue Anne ; Erlichman, Charles ; Liu, Fei Fei ; Miller, Naomi ; Pintilie, Melania. / Male breast cancer : An 11 year review of 66 patients. In: Breast Cancer Research and Treatment. 1996 ; Vol. 40, No. 3. pp. 225-230.
@article{eb83df128e7644ad9a3db4e5a9c1ffd5,
title = "Male breast cancer: An 11 year review of 66 patients",
abstract = "A review was conducted of 66 men with carcinoma of the breast seen at this institution between 1981 and 1992. The results of the study suggest that there are many similarities between breast cancer in men and women. The most common clinical presentation was a lump in the breast. The majority of tumors were T1 or T2, and infiltrating ductal carcinoma was the predominant histological type. Axillary nodal status and histological grade were predictive of survival. The pattern of recurrence and survival rates were similar to those seen in women. Some differences, however, were evident. Tumors were centrally located in the majority of patients and there was a high frequency of nipple involvement. The hormone receptor positivity rate was high and the median age at presentation was older. In comparison to a previous report of the same disease from this institution 10 years ago, fewer patients underwent radical surgical procedures and more patients received adjuvant systemic therapy. These approaches are justified since there are many biological similarities between breast cancer in men and women.",
keywords = "Breast cancer, Case series, Male",
author = "McLachlan, {Sue Anne} and Charles Erlichman and Liu, {Fei Fei} and Naomi Miller and Melania Pintilie",
year = "1996",
doi = "10.1007/BF01806810",
language = "English (US)",
volume = "40",
pages = "225--230",
journal = "Breast Cancer Research and Treatment",
issn = "0167-6806",
publisher = "Springer New York",
number = "3",

}

TY - JOUR

T1 - Male breast cancer

T2 - An 11 year review of 66 patients

AU - McLachlan, Sue Anne

AU - Erlichman, Charles

AU - Liu, Fei Fei

AU - Miller, Naomi

AU - Pintilie, Melania

PY - 1996

Y1 - 1996

N2 - A review was conducted of 66 men with carcinoma of the breast seen at this institution between 1981 and 1992. The results of the study suggest that there are many similarities between breast cancer in men and women. The most common clinical presentation was a lump in the breast. The majority of tumors were T1 or T2, and infiltrating ductal carcinoma was the predominant histological type. Axillary nodal status and histological grade were predictive of survival. The pattern of recurrence and survival rates were similar to those seen in women. Some differences, however, were evident. Tumors were centrally located in the majority of patients and there was a high frequency of nipple involvement. The hormone receptor positivity rate was high and the median age at presentation was older. In comparison to a previous report of the same disease from this institution 10 years ago, fewer patients underwent radical surgical procedures and more patients received adjuvant systemic therapy. These approaches are justified since there are many biological similarities between breast cancer in men and women.

AB - A review was conducted of 66 men with carcinoma of the breast seen at this institution between 1981 and 1992. The results of the study suggest that there are many similarities between breast cancer in men and women. The most common clinical presentation was a lump in the breast. The majority of tumors were T1 or T2, and infiltrating ductal carcinoma was the predominant histological type. Axillary nodal status and histological grade were predictive of survival. The pattern of recurrence and survival rates were similar to those seen in women. Some differences, however, were evident. Tumors were centrally located in the majority of patients and there was a high frequency of nipple involvement. The hormone receptor positivity rate was high and the median age at presentation was older. In comparison to a previous report of the same disease from this institution 10 years ago, fewer patients underwent radical surgical procedures and more patients received adjuvant systemic therapy. These approaches are justified since there are many biological similarities between breast cancer in men and women.

KW - Breast cancer

KW - Case series

KW - Male

UR - http://www.scopus.com/inward/record.url?scp=0029818454&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029818454&partnerID=8YFLogxK

U2 - 10.1007/BF01806810

DO - 10.1007/BF01806810

M3 - Article

C2 - 8883964

AN - SCOPUS:0029818454

VL - 40

SP - 225

EP - 230

JO - Breast Cancer Research and Treatment

JF - Breast Cancer Research and Treatment

SN - 0167-6806

IS - 3

ER -