Abstract
Fifty-eight patients with systemic lupus erythematosus (SLE) from Northern India were tissue typed for HLA class I and II antigens. The results revealed an appreciable increase of HLA-DR4 (37.5%) among patients compared with controls (17.9%), P < 0.03. Additionally, haplotype B8-DR3 was encountered frequently in the patient group. The findings suggest an important role of MHC genes in influencing susceptibility to SLE.
Original language | English (US) |
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Pages (from-to) | 313-314 |
Number of pages | 2 |
Journal | Lupus |
Volume | 2 |
Issue number | 5 |
DOIs | |
State | Published - Oct 1993 |
Keywords
- Asian Indians
- Major histocompatibility complex (MHC)
- SLE
ASJC Scopus subject areas
- Rheumatology