Major depression in coronary artery disease patients with vs. without a prior history of depression

K. E. Freedland, R. M. Carney, P. J. Lustman, M. W. Rich, Allan S Jaffe

Research output: Contribution to journalArticle

63 Citations (Scopus)

Abstract

Major depression (MD) is common in patients with coronary artery disease (CAD). Some of these patients have a history of prior depressive episodes, whereas others experience their first episode around the same time that their CAD is diagnosed. The purpose of this study was to determine whether there are systematic differences between these two subgroups of depressed patients. Of 39 patients with recently diagnosed CAD who met DSM-III-R criteria for MD, 17 (44%) had a prior history of MD. This subgroup had a higher proportion of females (p < 0.003), more severe depression (p < 0.004), were marginally younger (p = 0.08), and had slightly less severe CAD (p = 0.07) compared with those with no prior history of MD. These results support the hypothesis that there may be two distinctive subtypes of MD in patients with CAD. Additional studies are needed to determine whether these subgroups differ with respect to course, treatment, and relationship to the coronary artery disease.

Original languageEnglish (US)
Pages (from-to)416-421
Number of pages6
JournalPsychosomatic Medicine
Volume54
Issue number4
StatePublished - 1992
Externally publishedYes

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Coronary Artery Disease
Diagnostic and Statistical Manual of Mental Disorders
Therapeutics

Keywords

  • coronary disease
  • depression

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Psychology(all)

Cite this

Major depression in coronary artery disease patients with vs. without a prior history of depression. / Freedland, K. E.; Carney, R. M.; Lustman, P. J.; Rich, M. W.; Jaffe, Allan S.

In: Psychosomatic Medicine, Vol. 54, No. 4, 1992, p. 416-421.

Research output: Contribution to journalArticle

Freedland, KE, Carney, RM, Lustman, PJ, Rich, MW & Jaffe, AS 1992, 'Major depression in coronary artery disease patients with vs. without a prior history of depression', Psychosomatic Medicine, vol. 54, no. 4, pp. 416-421.
Freedland, K. E. ; Carney, R. M. ; Lustman, P. J. ; Rich, M. W. ; Jaffe, Allan S. / Major depression in coronary artery disease patients with vs. without a prior history of depression. In: Psychosomatic Medicine. 1992 ; Vol. 54, No. 4. pp. 416-421.
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