Abstract
Superficial fungal infections are fairly prevalent in transplant recipients and the incidence increases with more intense graft-conserving immunosuppressive therapy. Majocchi's granuloma is a deep folliculitis caused by dermatophytes that involves deeper layers of the dermis. Only a few case reports of the condition have been documented in transplant recipients. After an extensive review of the medical literature, 21 cases were retrieved and are summarized here, together with a new case that occurred in a recent heart transplant recipient from our institution. This report aims to provide a comprehensive analysis of Majocchi's granuloma in solid organ transplant (SOT) recipients, with special focus on potential risk factors, offending pathogens, clinical presentation, therapeutic approaches, and outcome. General observations are presented emphasizing the relevance of close clinical and dermatologic follow-up in high-risk SOT patients with specific comments regarding treatment regimens and outcomes.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 424-432 |
| Number of pages | 9 |
| Journal | Transplant Infectious Disease |
| Volume | 13 |
| Issue number | 4 |
| DOIs | |
| State | Published - Aug 2011 |
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Keywords
- Dermatophytes
- Fungal infection
- Granuloma
- Itraconazole
- Majocchi's granuloma
- Solid organ transplantation
- Transplantation
ASJC Scopus subject areas
- Transplantation
- Infectious Diseases
Cite this
Majocchi's granuloma in solid organ transplant recipients. / Romero, F. A.; Deziel, P. J.; Razonable, Raymund R.
In: Transplant Infectious Disease, Vol. 13, No. 4, 08.2011, p. 424-432.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Majocchi's granuloma in solid organ transplant recipients
AU - Romero, F. A.
AU - Deziel, P. J.
AU - Razonable, Raymund R
PY - 2011/8
Y1 - 2011/8
N2 - Superficial fungal infections are fairly prevalent in transplant recipients and the incidence increases with more intense graft-conserving immunosuppressive therapy. Majocchi's granuloma is a deep folliculitis caused by dermatophytes that involves deeper layers of the dermis. Only a few case reports of the condition have been documented in transplant recipients. After an extensive review of the medical literature, 21 cases were retrieved and are summarized here, together with a new case that occurred in a recent heart transplant recipient from our institution. This report aims to provide a comprehensive analysis of Majocchi's granuloma in solid organ transplant (SOT) recipients, with special focus on potential risk factors, offending pathogens, clinical presentation, therapeutic approaches, and outcome. General observations are presented emphasizing the relevance of close clinical and dermatologic follow-up in high-risk SOT patients with specific comments regarding treatment regimens and outcomes.
AB - Superficial fungal infections are fairly prevalent in transplant recipients and the incidence increases with more intense graft-conserving immunosuppressive therapy. Majocchi's granuloma is a deep folliculitis caused by dermatophytes that involves deeper layers of the dermis. Only a few case reports of the condition have been documented in transplant recipients. After an extensive review of the medical literature, 21 cases were retrieved and are summarized here, together with a new case that occurred in a recent heart transplant recipient from our institution. This report aims to provide a comprehensive analysis of Majocchi's granuloma in solid organ transplant (SOT) recipients, with special focus on potential risk factors, offending pathogens, clinical presentation, therapeutic approaches, and outcome. General observations are presented emphasizing the relevance of close clinical and dermatologic follow-up in high-risk SOT patients with specific comments regarding treatment regimens and outcomes.
KW - Dermatophytes
KW - Fungal infection
KW - Granuloma
KW - Itraconazole
KW - Majocchi's granuloma
KW - Solid organ transplantation
KW - Transplantation
UR - http://www.scopus.com/inward/record.url?scp=79961207556&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79961207556&partnerID=8YFLogxK
U2 - 10.1111/j.1399-3062.2010.00596.x
DO - 10.1111/j.1399-3062.2010.00596.x
M3 - Article
C2 - 21272168
AN - SCOPUS:79961207556
VL - 13
SP - 424
EP - 432
JO - Transplant Infectious Disease
JF - Transplant Infectious Disease
SN - 1398-2273
IS - 4
ER -