Majocchi's granuloma in solid organ transplant recipients

F. A. Romero, P. J. Deziel, R. R. Razonable

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

Superficial fungal infections are fairly prevalent in transplant recipients and the incidence increases with more intense graft-conserving immunosuppressive therapy. Majocchi's granuloma is a deep folliculitis caused by dermatophytes that involves deeper layers of the dermis. Only a few case reports of the condition have been documented in transplant recipients. After an extensive review of the medical literature, 21 cases were retrieved and are summarized here, together with a new case that occurred in a recent heart transplant recipient from our institution. This report aims to provide a comprehensive analysis of Majocchi's granuloma in solid organ transplant (SOT) recipients, with special focus on potential risk factors, offending pathogens, clinical presentation, therapeutic approaches, and outcome. General observations are presented emphasizing the relevance of close clinical and dermatologic follow-up in high-risk SOT patients with specific comments regarding treatment regimens and outcomes.

Original languageEnglish (US)
Pages (from-to)424-432
Number of pages9
JournalTransplant Infectious Disease
Volume13
Issue number4
DOIs
StatePublished - Aug 2011

Keywords

  • Dermatophytes
  • Fungal infection
  • Granuloma
  • Itraconazole
  • Majocchi's granuloma
  • Solid organ transplantation
  • Transplantation

ASJC Scopus subject areas

  • Infectious Diseases
  • Transplantation

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