MAIA under the microscope — bringing trial design into focus

Prashant Kapoor; S Vincent Rajkumar

doi:10.1038/s41571-019-0198-0

MAIA under the microscope — bringing trial design into focus

Prashant Kapoor, S Vincent Rajkumar

Hematology

Research output: Contribution to journal › Article

Abstract

Using the example of the recently reported phase III MAIA trial, we emphasize herein the requirement to dig deeper into trial designs and end points to determine their appropriateness for the questions at hand and to assess whether a benefit in terms of the primary end point — even if statistically significant and seemingly clinically meaningful — is sufficient to warrant a change in clinical practice.

Original language	English (US)
Journal	Nature Reviews Clinical Oncology
DOIs	https://doi.org/10.1038/s41571-019-0198-0
State	Published - Jan 1 2019

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ASJC Scopus subject areas

Oncology

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Kapoor, P., & Rajkumar, S. V. (2019). MAIA under the microscope — bringing trial design into focus. Nature Reviews Clinical Oncology. https://doi.org/10.1038/s41571-019-0198-0

MAIA under the microscope — bringing trial design into focus. / Kapoor, Prashant ; Rajkumar, S Vincent.

In: Nature Reviews Clinical Oncology, 01.01.2019.

Research output: Contribution to journal › Article

Kapoor, P & Rajkumar, SV 2019, 'MAIA under the microscope — bringing trial design into focus', Nature Reviews Clinical Oncology. https://doi.org/10.1038/s41571-019-0198-0

Kapoor P , Rajkumar SV. MAIA under the microscope — bringing trial design into focus. Nature Reviews Clinical Oncology. 2019 Jan 1. https://doi.org/10.1038/s41571-019-0198-0

Kapoor, Prashant ; Rajkumar, S Vincent. / MAIA under the microscope — bringing trial design into focus. In: Nature Reviews Clinical Oncology. 2019.

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Access to Document

10.1038/s41571-019-0198-0