Magnetic resonance-guided focused ultrasound surgery for leiomyoma-associated infertility

Esther V.A. Bouwsma; Krzysztof R. Gorny; Gina K. Hesley; Jani R. Jensen; Lisa G. Peterson; Elizabeth A. Stewart

doi:10.1016/j.fertnstert.2011.04.056

Magnetic resonance-guided focused ultrasound surgery for leiomyoma-associated infertility

Esther V.A. Bouwsma, Krzysztof R. Gorny, Gina K. Hesley, Jani R. Jensen, Lisa G. Peterson, Elizabeth A. Stewart

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

Objective: To describe magnetic resonance-guided focused ultrasound surgery (FUS) as a treatment for a case of leiomyoma-associated infertility. Design: Case report from a randomized clinical trial. Setting: Academic medical center. Patient(s): A 37-year-old woman with known leiomyomas and a history of 18 months of home-inseminations from a known donor. Intervention(s): Magnetic resonance-guided FUS treatment of uterine fibroids, where the dominant fibroid distorted the uterine cavity. Main Outcome Measure(s): Pregnancy. Result(s): A viable intrauterine pregnancy, with a full-term vaginal delivery, was conceived after a single clomiphene citrate and intrauterine insemination cycle. Conclusion(s): The role of FUS for enhancement of fertility in women with nonhysteroscopically resectable uterine fibroids distorting the uterine cavity should be investigated further.

Original language	English (US)
Pages (from-to)	e9-e12
Journal	Fertility and sterility
Volume	96
Issue number	1
DOIs	https://doi.org/10.1016/j.fertnstert.2011.04.056
State	Published - Jul 2011

Keywords

FUS
Fertility
MRgFUS
focused ultrasound
leiomyomas
pregnancy
randomized clinical trial

ASJC Scopus subject areas

Reproductive Medicine
Obstetrics and Gynecology

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10.1016/j.fertnstert.2011.04.056

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title = "Magnetic resonance-guided focused ultrasound surgery for leiomyoma-associated infertility",

abstract = "Objective: To describe magnetic resonance-guided focused ultrasound surgery (FUS) as a treatment for a case of leiomyoma-associated infertility. Design: Case report from a randomized clinical trial. Setting: Academic medical center. Patient(s): A 37-year-old woman with known leiomyomas and a history of 18 months of home-inseminations from a known donor. Intervention(s): Magnetic resonance-guided FUS treatment of uterine fibroids, where the dominant fibroid distorted the uterine cavity. Main Outcome Measure(s): Pregnancy. Result(s): A viable intrauterine pregnancy, with a full-term vaginal delivery, was conceived after a single clomiphene citrate and intrauterine insemination cycle. Conclusion(s): The role of FUS for enhancement of fertility in women with nonhysteroscopically resectable uterine fibroids distorting the uterine cavity should be investigated further.",

keywords = "FUS, Fertility, MRgFUS, focused ultrasound, leiomyomas, pregnancy, randomized clinical trial",

author = "Bouwsma, {Esther V.A.} and Gorny, {Krzysztof R.} and Hesley, {Gina K.} and Jensen, {Jani R.} and Peterson, {Lisa G.} and Stewart, {Elizabeth A.}",

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AU - Bouwsma, Esther V.A.

AU - Gorny, Krzysztof R.

AU - Hesley, Gina K.

AU - Jensen, Jani R.

AU - Peterson, Lisa G.

AU - Stewart, Elizabeth A.

PY - 2011/7

Y1 - 2011/7

N2 - Objective: To describe magnetic resonance-guided focused ultrasound surgery (FUS) as a treatment for a case of leiomyoma-associated infertility. Design: Case report from a randomized clinical trial. Setting: Academic medical center. Patient(s): A 37-year-old woman with known leiomyomas and a history of 18 months of home-inseminations from a known donor. Intervention(s): Magnetic resonance-guided FUS treatment of uterine fibroids, where the dominant fibroid distorted the uterine cavity. Main Outcome Measure(s): Pregnancy. Result(s): A viable intrauterine pregnancy, with a full-term vaginal delivery, was conceived after a single clomiphene citrate and intrauterine insemination cycle. Conclusion(s): The role of FUS for enhancement of fertility in women with nonhysteroscopically resectable uterine fibroids distorting the uterine cavity should be investigated further.

AB - Objective: To describe magnetic resonance-guided focused ultrasound surgery (FUS) as a treatment for a case of leiomyoma-associated infertility. Design: Case report from a randomized clinical trial. Setting: Academic medical center. Patient(s): A 37-year-old woman with known leiomyomas and a history of 18 months of home-inseminations from a known donor. Intervention(s): Magnetic resonance-guided FUS treatment of uterine fibroids, where the dominant fibroid distorted the uterine cavity. Main Outcome Measure(s): Pregnancy. Result(s): A viable intrauterine pregnancy, with a full-term vaginal delivery, was conceived after a single clomiphene citrate and intrauterine insemination cycle. Conclusion(s): The role of FUS for enhancement of fertility in women with nonhysteroscopically resectable uterine fibroids distorting the uterine cavity should be investigated further.

KW - FUS

KW - Fertility

KW - MRgFUS

KW - focused ultrasound

KW - leiomyomas

KW - pregnancy

KW - randomized clinical trial

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Magnetic resonance-guided focused ultrasound surgery for leiomyoma-associated infertility

Abstract

Keywords

ASJC Scopus subject areas

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