Magnetic resonance-guided focused ultrasound surgery for leiomyoma-associated infertility

Esther V A Bouwsma, Krzysztof R. Gorny, Gina K. Hesley, Jani R. Jensen, Lisa G. Peterson, Elizabeth A Stewart

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Objective: To describe magnetic resonance-guided focused ultrasound surgery (FUS) as a treatment for a case of leiomyoma-associated infertility. Design: Case report from a randomized clinical trial. Setting: Academic medical center. Patient(s): A 37-year-old woman with known leiomyomas and a history of 18 months of home-inseminations from a known donor. Intervention(s): Magnetic resonance-guided FUS treatment of uterine fibroids, where the dominant fibroid distorted the uterine cavity. Main Outcome Measure(s): Pregnancy. Result(s): A viable intrauterine pregnancy, with a full-term vaginal delivery, was conceived after a single clomiphene citrate and intrauterine insemination cycle. Conclusion(s): The role of FUS for enhancement of fertility in women with nonhysteroscopically resectable uterine fibroids distorting the uterine cavity should be investigated further.

Original languageEnglish (US)
JournalFertility and Sterility
Volume96
Issue number1
DOIs
StatePublished - Jul 2011

Fingerprint

Leiomyoma
Infertility
Magnetic Resonance Spectroscopy
Insemination
Pregnancy
Clomiphene
Fertility
Randomized Controlled Trials
Outcome Assessment (Health Care)
Tissue Donors
Therapeutics

Keywords

  • Fertility
  • focused ultrasound
  • FUS
  • leiomyomas
  • MRgFUS
  • pregnancy
  • randomized clinical trial

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Reproductive Medicine

Cite this

Magnetic resonance-guided focused ultrasound surgery for leiomyoma-associated infertility. / Bouwsma, Esther V A; Gorny, Krzysztof R.; Hesley, Gina K.; Jensen, Jani R.; Peterson, Lisa G.; Stewart, Elizabeth A.

In: Fertility and Sterility, Vol. 96, No. 1, 07.2011.

Research output: Contribution to journalArticle

Bouwsma, Esther V A ; Gorny, Krzysztof R. ; Hesley, Gina K. ; Jensen, Jani R. ; Peterson, Lisa G. ; Stewart, Elizabeth A. / Magnetic resonance-guided focused ultrasound surgery for leiomyoma-associated infertility. In: Fertility and Sterility. 2011 ; Vol. 96, No. 1.
@article{6b3c9f0a2c044bd5ba4899024e2c8f3d,
title = "Magnetic resonance-guided focused ultrasound surgery for leiomyoma-associated infertility",
abstract = "Objective: To describe magnetic resonance-guided focused ultrasound surgery (FUS) as a treatment for a case of leiomyoma-associated infertility. Design: Case report from a randomized clinical trial. Setting: Academic medical center. Patient(s): A 37-year-old woman with known leiomyomas and a history of 18 months of home-inseminations from a known donor. Intervention(s): Magnetic resonance-guided FUS treatment of uterine fibroids, where the dominant fibroid distorted the uterine cavity. Main Outcome Measure(s): Pregnancy. Result(s): A viable intrauterine pregnancy, with a full-term vaginal delivery, was conceived after a single clomiphene citrate and intrauterine insemination cycle. Conclusion(s): The role of FUS for enhancement of fertility in women with nonhysteroscopically resectable uterine fibroids distorting the uterine cavity should be investigated further.",
keywords = "Fertility, focused ultrasound, FUS, leiomyomas, MRgFUS, pregnancy, randomized clinical trial",
author = "Bouwsma, {Esther V A} and Gorny, {Krzysztof R.} and Hesley, {Gina K.} and Jensen, {Jani R.} and Peterson, {Lisa G.} and Stewart, {Elizabeth A}",
year = "2011",
month = "7",
doi = "10.1016/j.fertnstert.2011.04.056",
language = "English (US)",
volume = "96",
journal = "Fertility and Sterility",
issn = "0015-0282",
publisher = "Elsevier Inc.",
number = "1",

}

TY - JOUR

T1 - Magnetic resonance-guided focused ultrasound surgery for leiomyoma-associated infertility

AU - Bouwsma, Esther V A

AU - Gorny, Krzysztof R.

AU - Hesley, Gina K.

AU - Jensen, Jani R.

AU - Peterson, Lisa G.

AU - Stewart, Elizabeth A

PY - 2011/7

Y1 - 2011/7

N2 - Objective: To describe magnetic resonance-guided focused ultrasound surgery (FUS) as a treatment for a case of leiomyoma-associated infertility. Design: Case report from a randomized clinical trial. Setting: Academic medical center. Patient(s): A 37-year-old woman with known leiomyomas and a history of 18 months of home-inseminations from a known donor. Intervention(s): Magnetic resonance-guided FUS treatment of uterine fibroids, where the dominant fibroid distorted the uterine cavity. Main Outcome Measure(s): Pregnancy. Result(s): A viable intrauterine pregnancy, with a full-term vaginal delivery, was conceived after a single clomiphene citrate and intrauterine insemination cycle. Conclusion(s): The role of FUS for enhancement of fertility in women with nonhysteroscopically resectable uterine fibroids distorting the uterine cavity should be investigated further.

AB - Objective: To describe magnetic resonance-guided focused ultrasound surgery (FUS) as a treatment for a case of leiomyoma-associated infertility. Design: Case report from a randomized clinical trial. Setting: Academic medical center. Patient(s): A 37-year-old woman with known leiomyomas and a history of 18 months of home-inseminations from a known donor. Intervention(s): Magnetic resonance-guided FUS treatment of uterine fibroids, where the dominant fibroid distorted the uterine cavity. Main Outcome Measure(s): Pregnancy. Result(s): A viable intrauterine pregnancy, with a full-term vaginal delivery, was conceived after a single clomiphene citrate and intrauterine insemination cycle. Conclusion(s): The role of FUS for enhancement of fertility in women with nonhysteroscopically resectable uterine fibroids distorting the uterine cavity should be investigated further.

KW - Fertility

KW - focused ultrasound

KW - FUS

KW - leiomyomas

KW - MRgFUS

KW - pregnancy

KW - randomized clinical trial

UR - http://www.scopus.com/inward/record.url?scp=79959912830&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79959912830&partnerID=8YFLogxK

U2 - 10.1016/j.fertnstert.2011.04.056

DO - 10.1016/j.fertnstert.2011.04.056

M3 - Article

C2 - 21570071

AN - SCOPUS:79959912830

VL - 96

JO - Fertility and Sterility

JF - Fertility and Sterility

SN - 0015-0282

IS - 1

ER -