Magnetic resonance elastography of the liver

Sumeet K. Asrani, Jayant A. Talwalkar

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Elastography evaluates the intrinsic mechanical viscoelastic properties of liver parenchyma and allow for estimation of liver stiffness (LS), whereby elevated stiffness is associated with presence of advanced fibrosis. Measurement of liver stiffness by magnetic resonance elastography (MRE) has been tested for staging of liver disease in a variety of patients, providing convincing data especially among those with non-alcoholic fatty liver disease. Beyond diagnosis, non-invasive measures may have a prognostic role. Measurement of LS by MRE may serve as a complementary tool to monitor progression of disease. However, clinical algorithms are needed whereby MRE and other non-invasive markers can seamlessly be incorporated in care of patients with CLD, keeping in mind the cost, accessibility and incremental clinical utility offered above and beyond that which may be gained by simple bedside clinical assessment.

Original languageEnglish (US)
Title of host publicationDiagnostic Methods for Cirrhosis and Portal Hypertension
PublisherSpringer International Publishing
Pages225-238
Number of pages14
ISBN (Electronic)9783319726281
ISBN (Print)9783319726274
DOIs
StatePublished - Jan 1 2018

Keywords

  • Cirrhosis
  • Compensated
  • Decompensated
  • Magnetic resonance elastography
  • Portal hypertension
  • Prognosis
  • Serum tests
  • Transient elastography

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

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    Asrani, S. K., & Talwalkar, J. A. (2018). Magnetic resonance elastography of the liver. In Diagnostic Methods for Cirrhosis and Portal Hypertension (pp. 225-238). Springer International Publishing. https://doi.org/10.1007/978-3-319-72628-1_15