Magnetic resonance elastography (MRE) in cancer: Technique, analysis, and applications

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Tissue mechanical properties are significantly altered with the development of cancer. Magnetic resonance elastography (MRE) is a noninvasive technique capable of quantifying tissue mechanical properties in vivo. This review describes the basic principles of MRE and introduces some of the many promising MRE methods that have been developed for the detection and characterization of cancer, evaluation of response to therapy, and investigation of the underlying mechanical mechanisms associated with malignancy.

Original languageEnglish (US)
Pages (from-to)32-48
Number of pages17
JournalProgress in Nuclear Magnetic Resonance Spectroscopy
Volume90-91
DOIs
StatePublished - Jul 13 2015
Externally publishedYes

Fingerprint

Elasticity Imaging Techniques
Magnetic resonance
magnetic resonance
cancer
mechanical properties
Tissue
Neoplasms
Mechanical properties
therapy
evaluation
Therapeutics

Keywords

  • Clinical applications
  • Elasticity imaging
  • Magnetic resonance elastography (MRE)
  • Oncology
  • Tissue stiffness

ASJC Scopus subject areas

  • Analytical Chemistry
  • Spectroscopy
  • Nuclear and High Energy Physics
  • Materials Science(all)
  • Biochemistry

Cite this

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AU - McGee, Kiaran Patrick

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AB - Tissue mechanical properties are significantly altered with the development of cancer. Magnetic resonance elastography (MRE) is a noninvasive technique capable of quantifying tissue mechanical properties in vivo. This review describes the basic principles of MRE and introduces some of the many promising MRE methods that have been developed for the detection and characterization of cancer, evaluation of response to therapy, and investigation of the underlying mechanical mechanisms associated with malignancy.

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KW - Oncology

KW - Tissue stiffness

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