Magnetic resonance elastography for arterial wall characterization

Arunark Kolipaka, Richard D. White, Richard L. Ehman

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Aortic compliance and distensibility reflect overall wall stiffness, an extremely important and fundamental parameter altered in multiple diseases including hypertension, coronary artery disease, aortic aneurysm, and so on. Magnetic resonance elastography (MRE) is an innovative noninvasive imaging technique used to estimate the stiffness of soft tissues, including those comprising the wall of the aorta. This chapter describes (1) the principle of aortic MRE; (2) the motivation for use of aortic MRE for vascular applications; and (3) the current state-of-the-art in the development of aortic MRE, including the required hardware and MR pulse sequences. Finally, applications of aortic MRE and future potential application in characterizing coronary artery stiffness are also discussed.

Original languageEnglish (US)
Title of host publicationBiomechanics of Coronary Atherosclerotic Plaque
Subtitle of host publicationFrom Model to Patient
PublisherElsevier
Pages491-515
Number of pages25
ISBN (Electronic)9780128171950
ISBN (Print)9780128171967
DOIs
StatePublished - Jan 1 2021

Keywords

  • Abdominal aortic aneurysm
  • Aortic compliance
  • Aortic MRE
  • Aortic stiffness
  • Hypertension
  • Magnetic resonance elastography
  • Pulse wave velocity
  • Systemic arterial hypertension

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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