Magnetic resonance elastography by direct visualization of propagating acoustic strain waves

R. Muthupillai, D. J. Lomas, P. J. Rossman, James F Greenleaf, Armando Manduca, Richard Lorne Ehman

Research output: Contribution to journalArticle

1400 Citations (Scopus)

Abstract

A nuclear magnetic resonance imaging (MRI) method is presented for quantitatively mapping the physical response of a material to harmonic mechanical excitation. The resulting images allow calculation of regional mechanical properties. Measurements of shear modulus obtained with the MRI technique in gel materials correlate with independent measurements of static shear modulus. The results indicate that displacement patterns corresponding to cyclic displacements smaller than 200 nanometers can be measured. The findings suggest the feasibility of a medical imaging technique for delineating elasticity and other mechanical properties of tissue.

Original languageEnglish (US)
Pages (from-to)1854-1857
Number of pages4
JournalScience
Volume269
Issue number5232
StatePublished - Sep 29 1995

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Elasticity Imaging Techniques
Magnetic Resonance Imaging
Elasticity
Diagnostic Imaging
Magnetic Resonance Spectroscopy
Gels

ASJC Scopus subject areas

  • General

Cite this

Magnetic resonance elastography by direct visualization of propagating acoustic strain waves. / Muthupillai, R.; Lomas, D. J.; Rossman, P. J.; Greenleaf, James F; Manduca, Armando; Ehman, Richard Lorne.

In: Science, Vol. 269, No. 5232, 29.09.1995, p. 1854-1857.

Research output: Contribution to journalArticle

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