Magnetic resonance appearance of peripheral nerve sheath tumors

Margaret A. Stull, Richard P. Moser, Mark J. Kransdorf, George P. Bogumill, Martha C. Nelson

Research output: Contribution to journalArticle

152 Citations (Scopus)

Abstract

Magnetic resonance imaging (MRI) was used to evaluate 22 histologically proven peripheral nerve sheath tumors, approximately two-thirds of which arose in the lower extremity. The histologic distribution was as follows: 12 schwannomas, 7 neurofibromas, and 3 malignant peripheral nerve sheath tumors (2 of which occurred in patients with neurofibromatosis). Most lesions demonstrated an intermediate to moderately bright signal on T1-weighted images and were minimally inhomogeneous. All lesions were moderately bright on proton-density-weighted images and bright on T2-weighted images, again with variable inhomogeneity. The extent of the tumor was best assessed on proton-density- and T2-weighted images. Smooth margins were noted in 19 lesions. Of the 3 remaining lesions, 2 were malignant (but had been subjected to biopsy prior to MRI), and the other lesion was a plexiform neurofibroma. MRI accurately determined the relationship between the lesion and the adjacent neurovascular structures and muscles, thereby assisting surgical management. On MRI, 5 lesions demonstrated coexistent subtle muscle atrophy along the longitudinal axis of surrounding or distally innervated musculature. This latter finding, together with the presence of a tumor in the vicinity of a large nerve trunk, suggests a peripheral nerve sheath neoplasm.

Original languageEnglish (US)
Pages (from-to)9-14
Number of pages6
JournalSkeletal Radiology
Volume20
Issue number1
DOIs
StatePublished - Jan 1991
Externally publishedYes

Fingerprint

Nerve Sheath Neoplasms
Magnetic Resonance Spectroscopy
Magnetic Resonance Imaging
Neurilemmoma
Protons
Peripheral Nervous System Neoplasms
Plexiform Neurofibroma
Neurofibroma
Neurofibromatoses
Muscular Atrophy
Lower Extremity
Neoplasms
Biopsy
Muscles

Keywords

  • Magnetic resonance
  • Neural tumors
  • Peripheral nerves

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

Cite this

Stull, M. A., Moser, R. P., Kransdorf, M. J., Bogumill, G. P., & Nelson, M. C. (1991). Magnetic resonance appearance of peripheral nerve sheath tumors. Skeletal Radiology, 20(1), 9-14. https://doi.org/10.1007/BF00243714

Magnetic resonance appearance of peripheral nerve sheath tumors. / Stull, Margaret A.; Moser, Richard P.; Kransdorf, Mark J.; Bogumill, George P.; Nelson, Martha C.

In: Skeletal Radiology, Vol. 20, No. 1, 01.1991, p. 9-14.

Research output: Contribution to journalArticle

Stull, MA, Moser, RP, Kransdorf, MJ, Bogumill, GP & Nelson, MC 1991, 'Magnetic resonance appearance of peripheral nerve sheath tumors', Skeletal Radiology, vol. 20, no. 1, pp. 9-14. https://doi.org/10.1007/BF00243714
Stull MA, Moser RP, Kransdorf MJ, Bogumill GP, Nelson MC. Magnetic resonance appearance of peripheral nerve sheath tumors. Skeletal Radiology. 1991 Jan;20(1):9-14. https://doi.org/10.1007/BF00243714
Stull, Margaret A. ; Moser, Richard P. ; Kransdorf, Mark J. ; Bogumill, George P. ; Nelson, Martha C. / Magnetic resonance appearance of peripheral nerve sheath tumors. In: Skeletal Radiology. 1991 ; Vol. 20, No. 1. pp. 9-14.
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