Magnetic resonanace-guided focused ultrasound surgery of uterine leiomyomas

Fiona M. Fennessy, Elizabeth A Stewart, Clare Tempany

Research output: Contribution to journalArticle

Abstract

Uterine leiomyomas are the most common female pelvic tumor, are associated with menorrhagia or pressure-related issues such as fullness and urinary frequency, and are rarely a cause of infertility. Present-day treatment options include hysterectomy, myomectomy, uterine artery embolization, and hormonal therapy. Non-invasive magnetic resonance-guided focused ultrasound surgery (MRg FUS) has the potential to become a non-invasive choice for selected patients. This technique utilizes an effective combination of MR image guidance and energy delivery, thereby proposing an attractive method of non-invasive thermal ablation. Ultrasound waves are focused through intact skin of the anterior abdominal wall resulting in localized thermal tissue ablation, and focal areas of the leiomyoma undergo protein denaturation and coagulative necrosis.

Original languageEnglish (US)
Pages (from-to)171-176
Number of pages6
JournalJournal of Women's Imaging
Volume5
Issue number4
DOIs
StatePublished - Nov 2003
Externally publishedYes

Fingerprint

Leiomyoma
Uterine Myomectomy
Hot Temperature
Uterine Artery Embolization
Protein Denaturation
Menorrhagia
Abdominal Wall
Hysterectomy
Infertility
Necrosis
Magnetic Resonance Spectroscopy
Pressure
Skin
Therapeutics
Neoplasms
Ultrasonic Waves

Keywords

  • Focused ultrasound surgery (FUS)
  • Leiomyomas
  • Magnetic resonance imaging (MRI)
  • MRg FUS

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Radiology Nuclear Medicine and imaging

Cite this

Magnetic resonanace-guided focused ultrasound surgery of uterine leiomyomas. / Fennessy, Fiona M.; Stewart, Elizabeth A; Tempany, Clare.

In: Journal of Women's Imaging, Vol. 5, No. 4, 11.2003, p. 171-176.

Research output: Contribution to journalArticle

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