Macular edema is a rare finding in untreated vitreoretinal lymphoma: Small case series and review of the literature

Elisa Carreras, Diva R. Salomão, Jeroni Nadal, Sejal R. Amin, Harish Raja, Thomas J. Grube, Ryan L. Geraets, Patrick Bruce Johnston, Brian Patrick O'Neill, Jose S Pulido

Research output: Contribution to journalReview article

6 Scopus citations

Abstract

Background: To determine the occurrence of macular edema (ME) in vitreoretinal lymphoma (VRL). Methods: Retrospective analysis of 17 patients (31 eyes) with VRL. A review of the literature was done as well. Results: Nine patients (15 eyes) had fluorescein angiography and/or optical coherence tomography at presentation. In the ME group (six eyes of four patients), three patients (five eyes) had prior chemotherapy and radiation. Excluding eyes with radiation retinopathy (three eyes), rate of ME was 25% (3/12). When two unirradiated fellow eyes of eyes with radiation retinopathy were also excluded, ME rate was 10% (1/10). Excluding the eyes with intraocular surgery, the rate of ME was 0%. In the group without ME (nine eyes of six patients), one patient (one eye) was treated with chemotherapy and radiation and three patients (five eyes) with chemotherapy. Review of the literature showed that the ME was found between 2 and 60% of cases, but most of the cases with ME had prior interventions. Conclusions: Macular edema in VRL is not uncommon but usually related to prior interventions. Macular edema as an initial presentation of VRL is rare.

Original languageEnglish (US)
Article number15
JournalInternational Journal of Retina and Vitreous
Volume3
Issue number1
DOIs
StatePublished - Jan 1 2017

ASJC Scopus subject areas

  • Ophthalmology

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