Abstract
Originally described in the nasopharynx, lymphoepitheliomas are undifferentiated carcinomas with prominent lymphoid infiltration. Recently this tumor has been described in a number of other sites. An association with prior infection by the Epstein-Barr virus has been recognized in cases from the nasopharynx. We report four cases of lymphoepithelioma-like carcinoma arising in the lung. Epstein-Barr virus serology indicated prior infection in two cases, one of which was also found by in situ hybridization to have the virus genome. Lymphoepithelioma-like carcinoma must be considered in the differential diagnosis of primary lung tumors, particularly when an extensive infiltrate by lymphoid tissue is present and may even suggest lymphoma.
Original language | English (US) |
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Pages (from-to) | 632-639 |
Number of pages | 8 |
Journal | American Journal of Surgical Pathology |
Volume | 13 |
Issue number | 8 |
DOIs | |
State | Published - 1989 |
ASJC Scopus subject areas
- Anatomy
- Surgery
- Pathology and Forensic Medicine