TY - JOUR
T1 - Lymphocytic interstitial pneumonia
T2 - Thin-section CT findings in 22 patients
AU - Johkoh, Takeshi
AU - Müller, Nestor L.
AU - Pickford, Heather A.
AU - Hartman, Thomas E.
AU - Ichikado, Kazuya
AU - Akira, Masanori
AU - Honda, Osamu
AU - Nakamura, Hironobu
PY - 1999/8
Y1 - 1999/8
N2 - PURPOSE: To assess the thin-section computed tomographic (CT) findings of lymphocytic interstitial pneumonia. MATERIALS AND METHODS: The study included 22 patients (five men, 17 women; age range, 24-83 years; mean age, 50 years) with biopsy-proved lymphocytic interstitial pneumonia. The CT scans were obtained by using 1-3-mm collimation and reconstructed by using a high- spatial-frequency algorithm. RESULTS: The predominant abnormalities consisted of areas of ground-glass attenuation and poorly defined centrilobular nodules present in all 22 patients and subpleural small nodules seen in 19 patients. Other common findings included thickening of bronchovascular bundles (n = 19), interlobular septal thickening (n = 18), cystic airspaces (n = 15), and lymph node enlargement (n = 15). Less common findings included large nodules, emphysema, airspace consolidation, bronchiectasis, architectural distortion, honeycombing, and pleural thickening. CONCLUSION: Lymphocytic interstitial pneumonia is characterized by the presence of ground-glass attenuation, poorly defined centrilobular nodules, and thickening of the interstitium along the lymphatic vessels. Lymph node enlargement is more common than previously recognized; it was seen in 68% of patients.
AB - PURPOSE: To assess the thin-section computed tomographic (CT) findings of lymphocytic interstitial pneumonia. MATERIALS AND METHODS: The study included 22 patients (five men, 17 women; age range, 24-83 years; mean age, 50 years) with biopsy-proved lymphocytic interstitial pneumonia. The CT scans were obtained by using 1-3-mm collimation and reconstructed by using a high- spatial-frequency algorithm. RESULTS: The predominant abnormalities consisted of areas of ground-glass attenuation and poorly defined centrilobular nodules present in all 22 patients and subpleural small nodules seen in 19 patients. Other common findings included thickening of bronchovascular bundles (n = 19), interlobular septal thickening (n = 18), cystic airspaces (n = 15), and lymph node enlargement (n = 15). Less common findings included large nodules, emphysema, airspace consolidation, bronchiectasis, architectural distortion, honeycombing, and pleural thickening. CONCLUSION: Lymphocytic interstitial pneumonia is characterized by the presence of ground-glass attenuation, poorly defined centrilobular nodules, and thickening of the interstitium along the lymphatic vessels. Lymph node enlargement is more common than previously recognized; it was seen in 68% of patients.
KW - Acquired immunodeficiency syndrome (AIDS)
KW - Castleman disease
KW - Eye, diseases
KW - Lung, CT
KW - Pneumonitis, lymphocytic interstitial
KW - Sjogren syndrome
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U2 - 10.1148/radiology.212.2.r99au05567
DO - 10.1148/radiology.212.2.r99au05567
M3 - Article
C2 - 10429719
AN - SCOPUS:0344142482
SN - 0033-8419
VL - 212
SP - 567
EP - 572
JO - Radiology
JF - Radiology
IS - 2
ER -