Lymphocyte‐Mediated Antibody‐Dependent Cytolysis: Role in Immune Hemolysis

B. S. Handwerger, N. E. Kay, S. D. Douglas

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Abstract. Peripheral blood lymphocytes obtained from normal volunteers were capable of lysing Rh(D)‐positive human erythrocytes in the presence of IgG anti‐Rh(D) antibodies. The percent cytotoxicity produced by peripheral blood lymphocytes was approximately equivalent to that produced by unfractionated peripheral blood mononuclear cells. Neither peripheral blood mononuclear cells nor peripheral blood lymphocytes lysed Rh(D)‐negative human erythrocytes in the presence of IgG anti‐Rh(D) antibody.

Original languageEnglish (US)
Pages (from-to)276-280
Number of pages5
JournalVox Sanguinis
Volume34
Issue number5
DOIs
StatePublished - May 1978

ASJC Scopus subject areas

  • Hematology

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