Lymphocyte-mediated antibody-dependent cytolysis: role in immune hemolysis

B. S. Handwerger, Neil Elliot Kay, S. D. Douglas

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Peripheral blood lymphocytes obtained from normal volunteers were capable of lysing Rh(D)-positive human erythrocytes in the presence of IgG anti-Rh(D) antibodies. The percent cytotoxicity produced by peripheral blood lymphocytes was approximately equivalent to that produced by unfractionated peripheral blood mononuclear cells. Neither peripheral blood mononuclear cells nor peripheral blood lymphocytes lysed Rh(D)-negative human erythrocytes in the presence of IgG anti-Rh(D) antibody.

Original languageEnglish (US)
Pages (from-to)276-280
Number of pages5
JournalVox Sanguinis
Volume34
Issue number5
StatePublished - 1978
Externally publishedYes

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Hemolysis
Lymphocytes
Antibodies
Blood Cells
Immunoglobulin G
Erythrocytes
Healthy Volunteers
RHO(D) antibody

ASJC Scopus subject areas

  • Hematology

Cite this

Lymphocyte-mediated antibody-dependent cytolysis : role in immune hemolysis. / Handwerger, B. S.; Kay, Neil Elliot; Douglas, S. D.

In: Vox Sanguinis, Vol. 34, No. 5, 1978, p. 276-280.

Research output: Contribution to journalArticle

Handwerger, BS, Kay, NE & Douglas, SD 1978, 'Lymphocyte-mediated antibody-dependent cytolysis: role in immune hemolysis', Vox Sanguinis, vol. 34, no. 5, pp. 276-280.
Handwerger, B. S. ; Kay, Neil Elliot ; Douglas, S. D. / Lymphocyte-mediated antibody-dependent cytolysis : role in immune hemolysis. In: Vox Sanguinis. 1978 ; Vol. 34, No. 5. pp. 276-280.
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