Lymphangioleiomyomatosis (LAM)

Thomas Hartman

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Imaging description Lymphangioleiomyomatosis (LAM) is characterized on CT imaging by diffuse bilateral thin-walled cysts without a zonal predominance (Figures 11.1 and 11.2) [1–3]. LAM can affect just the lungs, but it can also be a systemic disease. Findings of pulmonary LAM are also seen associated with tuberous sclerosis. When LAM is systemic or associated with tuberous sclerosis additional findings can be present, the most common of which are angiomyolipomas of the kidneys (Figure 11.1) [2]. Adenopathy and dilated cystic masses can be seen in the abdomen and pelvis from obstructed lymphatics (lymphangioleiomyomas) [2]. Lymphatic obstruction can also result in chylous pleural effusions (Figure 11.3). Spontaneous pneumothorax occurs in 20%. Importance LAM is a progressive lung disease with a poor prognosis that typically affects women of childbearing age. In the appropriate clinical setting the CT findings are diagnostic.

Original languageEnglish (US)
Title of host publicationPearls and Pitfalls in Thoracic Imaging
Subtitle of host publicationVariants and Other Difficult Diagnoses
PublisherCambridge University Press
Pages26-29
Number of pages4
Volume9780521119078
ISBN (Electronic)9780511977701
ISBN (Print)9780521119078
DOIs
StatePublished - Jan 1 2011

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Hartman, T. (2011). Lymphangioleiomyomatosis (LAM). In Pearls and Pitfalls in Thoracic Imaging: Variants and Other Difficult Diagnoses (Vol. 9780521119078, pp. 26-29). Cambridge University Press. https://doi.org/10.1017/CBO9780511977701.012