Lung cancer and metastasis: new opportunities and challenges

Xiangdong Wang, Alex Adjei

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Lung cancer continues to attract special attention since the real number of lung cancer mortality and incidence in 2014 was definitely higher than those estimated numbers according to the report from World Health Organization. The present special issue highly focuses on advanced discovery and development of lung cancer and metastasis and discusses about potential opportunities and challenges to be faced. The present issue explores clinical applications of cancer immunotherapies, gene therapies, radiotherapies, or target-oriented therapies. A new and novel methodology can be used to identify differential interactions of driver genes, cancer-predictive genes, subtype-specific genes, or disease-exclusive genes or gene pairs from imbalanced or heterogeneous datasets. We also demonstrate the importance of lung cancer-specific gene mutations, epigenetics, gene sequencing, heterogeneity, or biomarker discovery. Clinical bioinformatics is emphasized as a critical tool and merging science. Novel therapies are designed and expected on basis of oncogenic molecular aberrations in lung cancer.

Original languageEnglish (US)
Pages (from-to)169-171
Number of pages3
JournalCancer and Metastasis Reviews
Volume34
Issue number2
DOIs
StatePublished - Jun 1 2015
Externally publishedYes

Fingerprint

Lung Neoplasms
Neoplasm Metastasis
Neoplasm Genes
Genes
Computational Biology
Epigenomics
Genetic Therapy
Immunotherapy
Radiotherapy
Biomarkers
Mutation
Mortality
Incidence
Therapeutics

Keywords

  • Biomarkers
  • Genomics
  • Lung cancer
  • Metastasis
  • Therapies

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Lung cancer and metastasis : new opportunities and challenges. / Wang, Xiangdong; Adjei, Alex.

In: Cancer and Metastasis Reviews, Vol. 34, No. 2, 01.06.2015, p. 169-171.

Research output: Contribution to journalArticle

@article{3d05ef6c65484935b207817ca8a7e5b1,
title = "Lung cancer and metastasis: new opportunities and challenges",
abstract = "Lung cancer continues to attract special attention since the real number of lung cancer mortality and incidence in 2014 was definitely higher than those estimated numbers according to the report from World Health Organization. The present special issue highly focuses on advanced discovery and development of lung cancer and metastasis and discusses about potential opportunities and challenges to be faced. The present issue explores clinical applications of cancer immunotherapies, gene therapies, radiotherapies, or target-oriented therapies. A new and novel methodology can be used to identify differential interactions of driver genes, cancer-predictive genes, subtype-specific genes, or disease-exclusive genes or gene pairs from imbalanced or heterogeneous datasets. We also demonstrate the importance of lung cancer-specific gene mutations, epigenetics, gene sequencing, heterogeneity, or biomarker discovery. Clinical bioinformatics is emphasized as a critical tool and merging science. Novel therapies are designed and expected on basis of oncogenic molecular aberrations in lung cancer.",
keywords = "Biomarkers, Genomics, Lung cancer, Metastasis, Therapies",
author = "Xiangdong Wang and Alex Adjei",
year = "2015",
month = "6",
day = "1",
doi = "10.1007/s10555-015-9562-4",
language = "English (US)",
volume = "34",
pages = "169--171",
journal = "Cancer and Metastasis Reviews",
issn = "0167-7659",
publisher = "Springer Netherlands",
number = "2",

}

TY - JOUR

T1 - Lung cancer and metastasis

T2 - new opportunities and challenges

AU - Wang, Xiangdong

AU - Adjei, Alex

PY - 2015/6/1

Y1 - 2015/6/1

N2 - Lung cancer continues to attract special attention since the real number of lung cancer mortality and incidence in 2014 was definitely higher than those estimated numbers according to the report from World Health Organization. The present special issue highly focuses on advanced discovery and development of lung cancer and metastasis and discusses about potential opportunities and challenges to be faced. The present issue explores clinical applications of cancer immunotherapies, gene therapies, radiotherapies, or target-oriented therapies. A new and novel methodology can be used to identify differential interactions of driver genes, cancer-predictive genes, subtype-specific genes, or disease-exclusive genes or gene pairs from imbalanced or heterogeneous datasets. We also demonstrate the importance of lung cancer-specific gene mutations, epigenetics, gene sequencing, heterogeneity, or biomarker discovery. Clinical bioinformatics is emphasized as a critical tool and merging science. Novel therapies are designed and expected on basis of oncogenic molecular aberrations in lung cancer.

AB - Lung cancer continues to attract special attention since the real number of lung cancer mortality and incidence in 2014 was definitely higher than those estimated numbers according to the report from World Health Organization. The present special issue highly focuses on advanced discovery and development of lung cancer and metastasis and discusses about potential opportunities and challenges to be faced. The present issue explores clinical applications of cancer immunotherapies, gene therapies, radiotherapies, or target-oriented therapies. A new and novel methodology can be used to identify differential interactions of driver genes, cancer-predictive genes, subtype-specific genes, or disease-exclusive genes or gene pairs from imbalanced or heterogeneous datasets. We also demonstrate the importance of lung cancer-specific gene mutations, epigenetics, gene sequencing, heterogeneity, or biomarker discovery. Clinical bioinformatics is emphasized as a critical tool and merging science. Novel therapies are designed and expected on basis of oncogenic molecular aberrations in lung cancer.

KW - Biomarkers

KW - Genomics

KW - Lung cancer

KW - Metastasis

KW - Therapies

UR - http://www.scopus.com/inward/record.url?scp=84938416069&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84938416069&partnerID=8YFLogxK

U2 - 10.1007/s10555-015-9562-4

DO - 10.1007/s10555-015-9562-4

M3 - Article

C2 - 25956388

AN - SCOPUS:84938416069

VL - 34

SP - 169

EP - 171

JO - Cancer and Metastasis Reviews

JF - Cancer and Metastasis Reviews

SN - 0167-7659

IS - 2

ER -