Lung biopsy in chronic lymphocytic leukemia

S. D. Rollins, T. V. Colby

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Nine patients with chronic lymphocytic leukemia (CLL), with pulmonary involvement confirmed by biopsy, presented with progressive cough and/or shortness of breath and had interstitial infiltrates on chest radiographs. Biopsies showed a dense lymphocytic infiltrate that followed bronchovascular bundles. We considered CLL the predominant finding, and the cause of the patient's pulmonary disease, in eight cases; in one, a histologically non-specific organizing pneumonia was the main lesion and CLL was an incidental finding. Culture results were available in six cases and were negative except in one case with presumed contaminants. A granulomatous reaction was present in five cases and was necrotizing in two, although culture results were negative. The only case with a recognizable organism had noninvasive fungal hyphae growing in many of the small airways. All of the patients' respiratory symptoms improved after chemotherapy and/or steroid therapy, and the chest radiographs also showed clearing.

Original languageEnglish (US)
Pages (from-to)607-611
Number of pages5
JournalArchives of Pathology and Laboratory Medicine
Volume112
Issue number6
StatePublished - 1988
Externally publishedYes

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B-Cell Chronic Lymphocytic Leukemia
Biopsy
Lung
Thorax
Incidental Findings
Hyphae
Cough
Dyspnea
Lung Diseases
Pneumonia
Steroids
Drug Therapy
Therapeutics

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

Cite this

Rollins, S. D., & Colby, T. V. (1988). Lung biopsy in chronic lymphocytic leukemia. Archives of Pathology and Laboratory Medicine, 112(6), 607-611.

Lung biopsy in chronic lymphocytic leukemia. / Rollins, S. D.; Colby, T. V.

In: Archives of Pathology and Laboratory Medicine, Vol. 112, No. 6, 1988, p. 607-611.

Research output: Contribution to journalArticle

Rollins, SD & Colby, TV 1988, 'Lung biopsy in chronic lymphocytic leukemia', Archives of Pathology and Laboratory Medicine, vol. 112, no. 6, pp. 607-611.
Rollins, S. D. ; Colby, T. V. / Lung biopsy in chronic lymphocytic leukemia. In: Archives of Pathology and Laboratory Medicine. 1988 ; Vol. 112, No. 6. pp. 607-611.
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