Low R-wave amplitude in the right precordial leads in children with symptomatic doxorubicin cardiomyopathy

Masakazu Umemoto, Eiichi Azuma, Masahiro Itoh, Yoshihiro Komada, Masaru Ido, Hajime Kawasaki, Hirohito Kita, Minoru Sakurai

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Electrocardiographic (ECG) findings were studied in four patients with doxorubicin cardiomyopathy. In all patients with congestive heart failure (CHF), the ECGs had a low R-wave and low R/S ratio in lead V1. Our study suggests that increased injury to myocardial cells in the regions of the anterior septum and anterior left ventricular wall may be important in the pathogenesis of doxorubicin cardiomyopathy. Eight years later, cardiac recovery from CHF occurred with a normal ECG and left ventricular ejection fraction in one patient, indicating that CHF may be reversible in certain cases.

Original languageEnglish (US)
Pages (from-to)107-109
Number of pages3
JournalPediatric Cardiology
Volume14
Issue number2
DOIs
StatePublished - Mar 1 1993

Keywords

  • Cardiomyopathy
  • Doxorubicin
  • Electrocardiogram

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Cardiology and Cardiovascular Medicine

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