Loss of sex and age driven differences in the gut microbiome characterize arthritis-susceptible *0401 mice but not arthritis-resistant *0402 mice

Medicine & Life Sciences

• Gastrointestinal Microbiome 80%
• Arthritis 71%
• Transgenic Mice 43%
• HLA-DRB1*04:02 antigen 33%
• HLA-DRB1*04:01 antigen 28%
• Rheumatoid Arthritis 27%
• Bacteria 22%
• Bifidobacterium 20%
• Clostridium 20%
• Experimental Arthritis 19%
• Gene Regulatory Networks 17%
• HLA-DR Antigens 17%
• Jejunum 17%
• rRNA Genes 17%
• 16S Ribosomal RNA 17%
• Microbiota 16%
• High-Throughput Nucleotide Sequencing 15%
• Sex Characteristics 15%
• Permeability 14%
• Genes 13%
• Joints 11%
• Biomarkers 10%
• Cytokines 10%
• Therapeutics 2%

Agriculture & Biology

• arthritis 100%
• microbiome 79%
• digestive system 66%
• gender 50%
• mice 47%
• rheumatoid arthritis 23%
• genetically modified organisms 20%
• Clostridium 10%
• Bifidobacterium 10%
• gene regulatory networks 10%
• bacteria 10%
• joints (animal) 9%
• jejunum 9%
• genes 9%
• genetic factors 9%
• intestinal microorganisms 9%
• gender differences 8%
• cytokines 8%
• pathogenesis 8%
• biomarkers 8%
• collagen 7%
• permeability 7%
• therapeutics 7%
• ribosomal RNA 6%
• methodology 2%

Chemical Compounds

• Biological Marker 73%
• Permeability 65%
• Resistance 51%
• Environment 46%