Longevity

Irene Maeve Rea, Giuseppina Candore, Luca Cavallone, Fabiola Olivieri, Maurizio Cardelli, Claudio Franceschi, Giuseppina Colonna-Romano, Domenico Lio, Owen A Ross, Calogero Caruso

Research output: Chapter in Book/Report/Conference proceedingChapter

10 Citations (Scopus)

Abstract

Life span is a multifactorial quantitative trait that is affected by genetic and environmental factors. It also contains a stochastic component resulting from the interaction between the individual’s chance of surviving and unpredictable events that occur throughout the life course. Advances in the treatment of fatal diseases and improvements in nutrition and living conditions led to a drastic reduction in death rate at young ages before 1950 and at old ages after 1950 in the developed world. As a result, mean life span has experienced a remarkable increase in developed countries.1 However, why some people live into their nineties or even become centenarians while others die earlier in life of infection, cancer, or inflammatory diseases such as atheroscelerosis, diabetes, or autoimmune disease remains largely unknown.

Original languageEnglish (US)
Title of host publicationCytokine Gene Polymorphisms in Multifactorial Conditions
PublisherCRC Press
Pages379-394
Number of pages16
ISBN (Electronic)9781420005325
ISBN (Print)0849336198, 9780849336195
StatePublished - Jan 1 2006
Externally publishedYes

Fingerprint

Nutrition
Medical problems
Social Conditions
Autoimmune Diseases
Mortality
Infection
Neoplasms
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)
  • Immunology and Microbiology(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Rea, I. M., Candore, G., Cavallone, L., Olivieri, F., Cardelli, M., Franceschi, C., ... Caruso, C. (2006). Longevity. In Cytokine Gene Polymorphisms in Multifactorial Conditions (pp. 379-394). CRC Press.

Longevity. / Rea, Irene Maeve; Candore, Giuseppina; Cavallone, Luca; Olivieri, Fabiola; Cardelli, Maurizio; Franceschi, Claudio; Colonna-Romano, Giuseppina; Lio, Domenico; Ross, Owen A; Caruso, Calogero.

Cytokine Gene Polymorphisms in Multifactorial Conditions. CRC Press, 2006. p. 379-394.

Research output: Chapter in Book/Report/Conference proceedingChapter

Rea, IM, Candore, G, Cavallone, L, Olivieri, F, Cardelli, M, Franceschi, C, Colonna-Romano, G, Lio, D, Ross, OA & Caruso, C 2006, Longevity. in Cytokine Gene Polymorphisms in Multifactorial Conditions. CRC Press, pp. 379-394.
Rea IM, Candore G, Cavallone L, Olivieri F, Cardelli M, Franceschi C et al. Longevity. In Cytokine Gene Polymorphisms in Multifactorial Conditions. CRC Press. 2006. p. 379-394
Rea, Irene Maeve ; Candore, Giuseppina ; Cavallone, Luca ; Olivieri, Fabiola ; Cardelli, Maurizio ; Franceschi, Claudio ; Colonna-Romano, Giuseppina ; Lio, Domenico ; Ross, Owen A ; Caruso, Calogero. / Longevity. Cytokine Gene Polymorphisms in Multifactorial Conditions. CRC Press, 2006. pp. 379-394
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