Longa-term outcome in occipital nerve stimulation patients with medically intractable primary headache disorders

Ann Chang Brewer, Terrence L. Trentman, Michael G. Ivancic, Bert B. Vargas, Alanna M. Rebecca, Richard S. Zimmerman, David M. Rosenfeld, David W. Dodick

Research output: Contribution to journalReview articlepeer-review

31 Scopus citations


Introduction:a- Occipital nerve stimulation (ONS) may provide relief for refractory headache disorders. However, scant data exist regarding longa-term ONS outcomes. Methods:a- The methods used were retrospective review of the medical records of all (nonindustry study) patients who were trialed and implanted with occipital nerve stimulator systems at our institution, followed by a phone interview. Up to three attempts were made to contact each patient, and those who were contacted were given the opportunity to participate in a brief phone interview regarding their ONS experience. Data for analysis were gleaned from both the phone interview and the patient's medical records. Results:a- Twentya-nine patients underwent a trial of ONS during the 8.5a-year study period. Three patients did not go on to permanent implant, 12 could not be contacted, and 14 participated in the phone interview. Based upon the phone interview (if the patient was contacted) or chart review, ONS was deemed successful in five of the 12 migraine, four of the five cluster headache, and five of the eight miscellaneous headache patients, and therapy was documented as long as 102 months. In one of the 26 patients, success of ONS could not be determined. Among patients deemed to have successful outcomes, headache frequency decreased by 18%, severity by 27%, and migraine disability score by 50%. Fiftya-eight percent of patients required at least one lead revision. Discussion:a- These results, although limited by their retrospective nature, suggest that ONS can be effective long term despite technical challenges. The number of patients within each headache subtype was insufficient to draw conclusions regarding the differential effect of ONS. Conclusions:a- Randomized controlled longa-term studies in specific, intractable, primary headache disorders are indicated.

Original languageEnglish (US)
Pages (from-to)557-564
Number of pages8
Issue number6
StatePublished - 2013


  • Cluster headache
  • headache
  • migraine
  • occipital nerve stimulation
  • peripheral nerve stimulation

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Anesthesiology and Pain Medicine


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