Long-time quality assessment of the Elecsys Troponin T hs assay

Ola Hammarsten, Carl Eric Jacobsson, Monica Widegren, Tatyana Danylchenko, Allan S Jaffe

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Recently, Roche announced a problem with the calibrators for their high sensitive cardiac troponin T (hscTnT) assay. We have monitored the performance of the assay since its introduction into clinical use in December 2009 and we're in a unique position to provide quantitative information concerning the effects of this problem. Our data document that the measured cTnT concentration in the hscTnT assay dropped by 5.8. ng/L around the 99th percentile before its recalibration in May 2012. Thus, the hscTnT levels in our hospital have been underestimated around this cut-off value since its introduction. The approach we used may be one that other laboratories should consider.

Original languageEnglish (US)
Pages (from-to)1055-1057
Number of pages3
JournalClinical Biochemistry
Volume46
Issue number12
DOIs
StatePublished - Aug 2013

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Troponin T
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Keywords

  • Calibration
  • High sensitive troponin assays

ASJC Scopus subject areas

  • Clinical Biochemistry

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Long-time quality assessment of the Elecsys Troponin T hs assay. / Hammarsten, Ola; Jacobsson, Carl Eric; Widegren, Monica; Danylchenko, Tatyana; Jaffe, Allan S.

In: Clinical Biochemistry, Vol. 46, No. 12, 08.2013, p. 1055-1057.

Research output: Contribution to journalArticle

Hammarsten, O, Jacobsson, CE, Widegren, M, Danylchenko, T & Jaffe, AS 2013, 'Long-time quality assessment of the Elecsys Troponin T hs assay', Clinical Biochemistry, vol. 46, no. 12, pp. 1055-1057. https://doi.org/10.1016/j.clinbiochem.2013.03.022
Hammarsten, Ola ; Jacobsson, Carl Eric ; Widegren, Monica ; Danylchenko, Tatyana ; Jaffe, Allan S. / Long-time quality assessment of the Elecsys Troponin T hs assay. In: Clinical Biochemistry. 2013 ; Vol. 46, No. 12. pp. 1055-1057.
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