TY - JOUR
T1 - Long-time quality assessment of the Elecsys Troponin T hs assay
AU - Hammarsten, Ola
AU - Jacobsson, Carl Eric
AU - Widegren, Monica
AU - Danylchenko, Tatyana
AU - Jaffe, Allan S.
PY - 2013/8
Y1 - 2013/8
N2 - Recently, Roche announced a problem with the calibrators for their high sensitive cardiac troponin T (hscTnT) assay. We have monitored the performance of the assay since its introduction into clinical use in December 2009 and we're in a unique position to provide quantitative information concerning the effects of this problem. Our data document that the measured cTnT concentration in the hscTnT assay dropped by 5.8. ng/L around the 99th percentile before its recalibration in May 2012. Thus, the hscTnT levels in our hospital have been underestimated around this cut-off value since its introduction. The approach we used may be one that other laboratories should consider.
AB - Recently, Roche announced a problem with the calibrators for their high sensitive cardiac troponin T (hscTnT) assay. We have monitored the performance of the assay since its introduction into clinical use in December 2009 and we're in a unique position to provide quantitative information concerning the effects of this problem. Our data document that the measured cTnT concentration in the hscTnT assay dropped by 5.8. ng/L around the 99th percentile before its recalibration in May 2012. Thus, the hscTnT levels in our hospital have been underestimated around this cut-off value since its introduction. The approach we used may be one that other laboratories should consider.
KW - Calibration
KW - High sensitive troponin assays
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U2 - 10.1016/j.clinbiochem.2013.03.022
DO - 10.1016/j.clinbiochem.2013.03.022
M3 - Article
C2 - 23578743
AN - SCOPUS:84880590520
SN - 0009-9120
VL - 46
SP - 1055
EP - 1057
JO - Clinical Biochemistry
JF - Clinical Biochemistry
IS - 12
ER -