Long-term survival after traumatic brain injury: A population-based analysis controlled for nonhead trauma

Allen W Brown, Cynthia L. Leibson, Jayawant Mandrekar, Jeanine E. Ransom, James F. Malec

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

OBJECTIVE: To examine the contribution of cooccurring nonhead injuries to hazard of death after traumatic brain injury (TBI). PARTICIPANTS: A random sample of Olmsted County, Minnesota, residents with confirmed TBI from 1987 through 1999 was identified. DESIGN: Each case was assigned an age- and sex-matched, non-TBI "regular control" from the population. For "special cases" with accompanying nonhead injuries, 2 matched "special controls" with nonhead injuries of similar severity were assigned. MEASURES: Vital status was followed from baseline (ie, injury date for cases, comparable dates for controls) through 2008. Cases were compared first with regular controls and second with regular or special controls, depending on case type. RESULTS: In total, 1257 cases were identified (including 221 special cases). For both cases versus regular controls and cases versus regular or special controls, the hazard ratio was increased from baseline to 6 months (10.82 [2.86-40.89] and 7.13 [3.10-16.39], respectively) and from baseline through study end (2.92 [1.74-4.91] and 1.48 [1.09-2.02], respectively). Among 6-month survivors, the hazard ratio was increased for cases versus regular controls (1.43 [1.06-2.15]) but not for cases versus regular or special controls (1.05 [0.80-1.38]). CONCLUSIONS: Among 6-month survivors, accounting for nonhead injuries resulted in a nonsignificant effect of TBI on long-term mortality.

Original languageEnglish (US)
JournalJournal of Head Trauma Rehabilitation
Volume29
Issue number1
DOIs
StatePublished - Jan 2014

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Survival
Wounds and Injuries
Population
Survivors
Safety Management
Brain Injuries
Traumatic Brain Injury
Mortality

ASJC Scopus subject areas

  • Rehabilitation
  • Clinical Neurology
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Long-term survival after traumatic brain injury : A population-based analysis controlled for nonhead trauma. / Brown, Allen W; Leibson, Cynthia L.; Mandrekar, Jayawant; Ransom, Jeanine E.; Malec, James F.

In: Journal of Head Trauma Rehabilitation, Vol. 29, No. 1, 01.2014.

Research output: Contribution to journalArticle

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